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WHO Guidelines on Hand Hygiene in Health Care - Safe Care ...

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<str<strong>on</strong>g>WHO</str<strong>on</strong>g> GUIDELINES ON HAND HYGIENE IN HEALTH CARE<br />

Table I.11.8<br />

Hygienic handrub efficacy of various agents <strong>in</strong> reduc<strong>in</strong>g the release of test bacteria from artificially-c<strong>on</strong>tam<strong>in</strong>ated hands<br />

Agent<br />

C<strong>on</strong>centrati<strong>on</strong> a<br />

(%)<br />

Test bacterium<br />

Mean log reducti<strong>on</strong> exposure time<br />

(m<strong>in</strong>)<br />

0.5 1.0 2.0<br />

n-Propanol 100<br />

60<br />

E. coli 5.8<br />

5.5<br />

50 5.0<br />

3.7 4.7 4.9<br />

40 4.3<br />

Isopropanol 70 E. coli 4.9<br />

4.8<br />

3.5<br />

60 4.4<br />

4.3<br />

4.2<br />

4.0<br />

S. marcescens 4.1<br />

50<br />

E. coli<br />

3.4 3.9 4.4<br />

Ethanol 80 E. coli 4.5<br />

70 4.3 5.1<br />

4.3 4.9<br />

4.0<br />

3.6 3.8 4.5<br />

3.4 4.1<br />

S. aureus 3.7<br />

2.6<br />

Tosylchloramide (aq. sol.) 60 S. saprophyticus 3.5 3.8<br />

Povid<strong>on</strong>e-iod<strong>in</strong>e (aq. sol.) 2.0 b E. coli 4.2<br />

Chlorhexid<strong>in</strong>e diacetate (aq. sol.)<br />

1.0 b<br />

E. coli<br />

0.5 b E. coli<br />

4.0–4.3<br />

3.1<br />

Chloro-cresol (aq. sol.) 1.0 b E. coli 3.6<br />

Hydrogen peroxide 7.5 E. coli 3.6<br />

a<br />

If not stated otherwise, v/v.<br />

b<br />

m/v.<br />

Sources: repr<strong>in</strong>ted with permissi<strong>on</strong> from Rotter, 2004. 480,481<br />

46

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