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Saponins, like lectins, phytic acid, and even fiber, are common in plant<br />

ingredients and can exert harm if isolated and given in extraordinarily<br />

high dosages. But as these ingredients exist within the integrated<br />

complex of whole, natural foods at natural low levels, they can exert<br />

many beneficial effects. For example, various compounds belonging<br />

to the class known as saponins, such as triterpen oligoglycosides,<br />

elatosides, escins, and senegasaponins are being studied because of<br />

their ability to treat cancer, hypercholesterolemia (In one review of 38<br />

clinical studies over a period of 17 years, involving 730 volunteers,<br />

blood lipid profiles [cholesterol, triglycerides, HDL, LDL, etc.] were<br />

improved.), diabetes, alcoholism, and inflammatory conditions. Saponins<br />

have the ability to slow the digestion of complex carbohydrates<br />

such as starch, which tends to moderate blood sugar levels,<br />

and even decrease the absorption of alcohol. Through this action it is<br />

believed that saponins may actually help prevent, as well as treat,<br />

blood sugar abnormalities. 1<br />

Other concerns related to soy include antinutritional factors such as<br />

enzyme inhibitors, hemagglutinins, and phytase. In sufficient dosages<br />

these compounds can interfere with digestion, promote blood clotting,<br />

and bind minerals. But again, the key is dosage. Properly<br />

processed soy (such as by high temperature, short time extrusion),<br />

eaten in variety with other nutritious ingredients, produces health rather<br />

than disease.<br />

A class of beneficial soy compounds is isoflavones, including genistein,<br />

which has estrogenic (female hormone) activity. <strong>The</strong>se phytoestrogens<br />

can counteract the carcinogenic effect of environmental estrogenic<br />

substances to which we, and our pets, are increasingly exposed. 2 Soy<br />

phytoestrogens can inhibit cancer-causing estrogen receptors in breast<br />

tissue, testosterone-sensitive prostate cancers, and suppress angiogenesis<br />

(blood vessel formation) in tumors. 3<br />

1. Science News, December 9 1995; 148. J Nutr, 2001; 131(3s):1000S-5S. J Nutr,<br />

1995; 125(3 Suppl):581S-588S. Rocz Panstw Zakl Hig, 1994; 45(1-2):125-30.<br />

Ceska Slov Farm, 1995; 44(5):246-51.<br />

2. Wysong Health Letter, “Feminization of the World,” 1994; 8(3). Lancet,<br />

1994:284.<br />

3. Wysong Health Letter, “Soy As <strong>The</strong>rapy,” 1999; 13(3). Arterioscl Thromb<br />

Vasc Biol, 1997; 17:2524-31. Am J Clin Nutr, 1997; 65:166-71. J Agric Food<br />

Chem, 1997; 45:4635-8. Lancet, 1997; 350:990-4. Nutr Cancer, 1997; 27:31-<br />

40. Proc Natl Acad Sci USA, 1998; 95:3106-10.<br />

PAGE 143

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