Corporate Governance <strong>Report</strong>The Board’s annual performance evaluation was previously externallyfacilitated in <strong>20</strong>08. The Board intends to continue to comply with theUK Corporate Governance Code guidance that the evaluation shouldbe externally facilitated at least every three years.Re-election of DirectorsIn accordance with Article 66 of the Articles, all Directors retire ateach AGM <strong>and</strong> may offer themselves for re-election by shareholders.Accordingly, all the Directors will retire at the AGM in April <strong>20</strong>12. TheNotice of AGM will give details of those Directors seeking re-election.AccountabilityRisk management <strong>and</strong> internal controlThe Non-Executive Directors have various responsibilitiesconcerning the integrity of financial information, internal controls<strong>and</strong> risk management.The Board has overall responsibility for our system of internal controls<strong>and</strong> risk management policies <strong>and</strong> is also responsible for reviewingtheir effectiveness. During <strong>20</strong>11, the Directors have continued toreview the effectiveness of our system of controls, risk management<strong>and</strong> our high-level internal control processes. These reviews haveincluded an assessment of internal controls, <strong>and</strong> in particular, financial,operational <strong>and</strong> compliance controls <strong>and</strong> risk management <strong>and</strong>their effectiveness, supported by management assurance of themaintenance of controls reports from GIA, as well as the externalauditor on matters identified in the course of its statutory audit work.The system is designed to manage rather than eliminate the risk offailure to achieve business objectives <strong>and</strong> can only provide reasonable(not necessarily absolute) assurance of effective operation <strong>and</strong>compliance with laws <strong>and</strong> regulations.Underpinning these reviews is an annual ‘letter of assurance’ processby which responsible managers confirm the adequacy of their systemsof internal financial <strong>and</strong> non-financial controls, their compliance withGroup policies <strong>and</strong> relevant laws <strong>and</strong> regulations (including theindustry’s regulatory requirements), <strong>and</strong> that they have reported anycontrol weaknesses through our ‘continuous assurance’ process.The internal control framework has been in operation throughout <strong>20</strong>11<strong>and</strong> continues to operate up to the date of the approval of this <strong>Annual</strong><strong>Report</strong>. The Directors believe that the Group maintains an effective,embedded system of internal controls <strong>and</strong> complies with the Turnbull<strong>Report</strong> guidance <strong>and</strong>, in the view of the Directors, no significantdeficiencies have been identified in the system.Further information about the ways in which we manage our businessrisks is set out in the Risk section from page 129, which also containsa list of the principal risks <strong>and</strong> uncertainties that we face.Remuneration<strong>Information</strong> about our approach to remuneration <strong>and</strong> the role <strong>and</strong>work of the Remuneration Committee, including our policy onexecutive remuneration, is set out in the Directors’ Remuneration<strong>Report</strong> from page 113.Relations with shareholdersIn our financial <strong>and</strong> business reporting to shareholders <strong>and</strong> otherinterested parties by means of quarterly, half-yearly <strong>and</strong> annualreports, we aim to present a balanced <strong>and</strong> underst<strong>and</strong>ableassessment of our strategy, financial position <strong>and</strong> prospects.We make information about the Group available to shareholdersthrough a range of media, including a fully integrated html corporatewebsite, astrazeneca.com, containing a wide range of data of interestto institutional <strong>and</strong> private investors. We consider our website to be animportant means of communication with our shareholders.The Company has been authorised by shareholders to placeshareholder communications (such as the Notice of AGM <strong>and</strong> this<strong>Annual</strong> <strong>Report</strong>) on the corporate website in lieu of sending papercopies to shareholders (unless specifically requested by shareholders).While recognising <strong>and</strong> respecting the fact that some of ourshareholders may have different preferences about how they receiveinformation from us, we will continue to promote the benefits ofelectronic communication given the advantages that this has overtraditional paper-based communications, both in terms of theconfigurability <strong>and</strong> accessibility of the information provided <strong>and</strong> theconsequent cost savings <strong>and</strong> reduction in environmental impactassociated with reduced printing <strong>and</strong> distribution costs.We have frequent discussions with institutional shareholders on arange of issues. These include individual meetings with some of ourlargest institutional shareholders to seek their views. Board membersare kept informed of any issues <strong>and</strong> receive regular reports <strong>and</strong>presentations from executive management <strong>and</strong> our brokers in orderto assist them to develop an underst<strong>and</strong>ing of major shareholders’views about the Group. From time to time, we conduct an audit ofinstitutional shareholders to ensure that we are communicating clearlywith them <strong>and</strong> that a high-quality dialogue is being maintained. Theresults of this audit are reported to <strong>and</strong> discussed by the full Board.In November, we invited corporate governance representatives fromour largest institutional shareholders to a meeting attended by LouisSchweitzer, Chairman of the Board; Michele Hooper, seniorindependent Non-Executive Director <strong>and</strong> Chairman of the AuditCommittee; John Varley, Chairman of the Remuneration Committee;<strong>and</strong> Rudy Markham, member of the Remuneration Committee <strong>and</strong>the Audit Committee. Although the meeting was primarily focusedon executive remuneration matters, it provided an opportunity forshareholders to raise any broader corporate governance issues fordiscussion as well.Board Committee membershipName Audit RemunerationNomination <strong>and</strong>Governance Science Independent 1David Brennann/aBruce Burlington 3 3 3Jean-Philippe Courtois 3 3Jane Henney 2 3 3 3 3Michele Hooper 3 Chair 3 3Simon Lowthn/aRudy Markham 3 3 3Nancy Rothwell 3 3 Chair 3Louis Schweitzer 4 3 Chair n/aShriti Vadera 3 3John Varley Chair 3 3Marcus Wallenberg 3 ✘1As determined by the Board for UK Corporate Governance Code purposes.2Jane Henney retired from the Board on 28 April <strong>20</strong>11.3Michele Hooper is the senior independent Non-Executive Director.4Louis Schweitzer was considered independent by the Board upon his appointment as Chairman. In accordance with the UK Corporate Governance Code, the test of independence is not appropriatein relation to the Chairman after his appointment.106 Corporate Governance <strong>Report</strong><strong>AstraZeneca</strong> <strong>Annual</strong> <strong>Report</strong> <strong>and</strong> <strong>Form</strong> <strong>20</strong>-F <strong>Information</strong> <strong>20</strong>11
We also respond to individual ad hoc requests for discussions frominstitutional shareholders <strong>and</strong> analysts. Our Investor Relations teamacts as the main point of contact for investors throughout the year.As discussed above, the senior independent Non-Executive Director,currently Michele Hooper, is also available to shareholders if they haveconcerns that contact through the normal channels of Chairman, CEO<strong>and</strong>/or CFO has failed to resolve, or in relation to which such contact isinappropriate. All shareholders, including private investors, have anopportunity at the AGM to put questions to members of the Boardabout our operation <strong>and</strong> performance. <strong>Form</strong>al notification of the AGMis sent to shareholders at least one month in advance. The Chairmenof the Board Committees ordinarily attend the AGM to answerquestions raised by shareholders. In line with the UK CorporateGovernance Code, details of proxy voting by shareholders, includingvotes withheld, are given at the AGM <strong>and</strong> are posted on our websitefollowing the AGM.Audit CommitteeThe members of the Audit Committee are Michele Hooper (Chairmanof the Audit Committee), Jean-Philippe Courtois, Rudy Markham,Shriti Vadera, Bruce Burlington, <strong>and</strong> until her retirement at the <strong>20</strong>11AGM, Jane Henney. They are (or in the case of Jane Henney, were) allNon-Executive Directors. The Board considers each member to beindependent under the UK Corporate Governance Code <strong>and</strong> underthe general guidance <strong>and</strong> specific criteria of the Listing St<strong>and</strong>ardsconcerning the composition of audit committees applicable to non-UScompanies listed on the NYSE. In April <strong>20</strong>11, we submitted therequired annual written affirmation to the NYSE confirming our fullcompliance with those st<strong>and</strong>ards. For the purposes of the UKCorporate Governance Code, the Board remains satisfied that at leastone member of the Audit Committee has recent <strong>and</strong> relevant financialexperience. At its meeting in December, the Board determined thatMichele Hooper <strong>and</strong> Rudy Markham are audit committee financialexperts for the purposes of the Sarbanes-Oxley Act. The DeputyCompany Secretary acts as secretary to the Audit Committee.The core terms of reference of the Audit Committee include, reviewing<strong>and</strong> reporting to the Board on:> Matters relating to the audit plans of the external auditor <strong>and</strong> GIAas well as oversight of the work of the Global Compliance function.> Our overall framework for internal control over financial reporting<strong>and</strong> for other internal controls <strong>and</strong> processes.> Our overall framework for risk management, particularlyfinancial risks.> Our accounting policies <strong>and</strong> practices.> Our annual <strong>and</strong> quarterly financial reporting, including the criticalestimates <strong>and</strong> judgements contained in our reporting.> Compliance with the Corporate Integrity Agreement (CIA).The Audit Committee is responsible for notifying the Board of anysignificant concerns of the external auditor or the Vice-President, GIAarising from their audit work, any matters that may materially affector impair the independence of the external auditor, any significantdeficiencies or material weaknesses in the design or operation of ourinternal control over financial reporting or other internal controls, <strong>and</strong>any serious issues of non-compliance. It oversees the establishment,implementation <strong>and</strong> maintenance of our Code of Conduct <strong>and</strong> otherrelated policies. It monitors the Company’s response to lettersrequesting information <strong>and</strong> investigations initiated by regulatory <strong>and</strong>governmental authorities such as the SEC <strong>and</strong> the US Department ofJustice pertaining to matters within the remit of the Audit Committee’swork. It has established procedures for the receipt <strong>and</strong> h<strong>and</strong>ling ofcomplaints concerning accounting or audit matters. It recommendsto the Board the appointment of the external auditor, subject to theapproval of the Company’s shareholders at a general meeting.Shareholders in a general meeting authorise the Directors to fix theremuneration of the external auditor. The Audit Committee reviews <strong>and</strong>approves the appointment <strong>and</strong> dismissal of the Vice-President, GIA.The Audit Committee maintains policies <strong>and</strong> procedures for thepre-approval of all audit services <strong>and</strong> permitted non-audit servicesundertaken by the external auditor, the principal purpose of whichis to ensure that the independence of the external auditor is notimpaired. The policies <strong>and</strong> procedures cover three categories of work– audit services, audit-related services <strong>and</strong> tax services. The policiesdefine the type of work that falls within each of these categories <strong>and</strong>the non-audit services that the external auditor is prohibited fromperforming under the rules of the SEC <strong>and</strong> other relevant UK <strong>and</strong>US professional <strong>and</strong> regulatory requirements. The pre-approvalprocedures permit certain audit, audit-related <strong>and</strong> tax services to beperformed by the external auditor during the year, subject to fee limitsagreed with the Audit Committee in advance. The CFO (supported bythe Vice-President, Group Finance) monitors the status of all servicesbeing provided by the external auditor. The procedures also deal withplacing non-audit work out for tender, where appropriate. Authority toapprove work in excess of the pre-agreed fee limits is delegated tothe Chairman of the Audit Committee in the first instance. A st<strong>and</strong>ingagenda item at Audit Committee meetings covers the operation of thepre-approval procedures <strong>and</strong> regular reports are provided to the fullAudit Committee.The Audit Committee held six scheduled meetings in <strong>20</strong>11. Theindividual attendance record of members of the Audit Committee isset out in the Board <strong>and</strong> Board Committee meeting attendance in<strong>20</strong>11 table on page 105. Following each Audit Committee meeting,the Chairman of the Audit Committee reported to the Board on theprincipal matters covered at the meeting <strong>and</strong> minutes of the meetingswere circulated to all Board members. In addition, the Chairmanof the Audit Committee held regular scheduled calls betweenAudit Committee meetings with each of the Vice-President, GIA,the Chief Compliance Officer, the CFO <strong>and</strong> the lead partner of theexternal auditor.During <strong>20</strong>11, members of the Audit Committee met individualmanagers or groups of managers on a number of occasions in orderto gain a deeper insight into areas relevant to the Audit Committee’swork <strong>and</strong> to provide an opportunity to discuss specific areas ofinterest. In particular, members of the Audit Committee travelled to ourmarketing companies in Brazil <strong>and</strong> Russia as well as to our marketingcompany, <strong>and</strong> R&D <strong>and</strong> manufacturing sites in China to meet seniorleaders in these important Emerging Markets. During these visits,Audit Committee members were able to gain a greater underst<strong>and</strong>ingof the unique business <strong>and</strong> cultural dynamics of each of these markets<strong>and</strong> to hear how our local operations meet the challenges presentedby these developing economies within the context of our globalcompliance framework.During the year, in line with its normal practice, the Audit Committeealso held a number of private meetings, without management present,with the Vice-President, GIA, the Global Compliance Officer (<strong>and</strong>following her appointment, the Chief Compliance Officer, whichposition replaced the Global Compliance Officer), the General Counsel<strong>and</strong> the lead partner from the Company’s external audit firm. Thepurpose of these meetings was to facilitate free <strong>and</strong> open discussionsbetween Audit Committee members <strong>and</strong> those individuals, separatelyfrom the main sessions of the Audit Committee, which were alsoattended by the CEO, the CFO, the General Counsel <strong>and</strong> theVice-President, Group Finance.Corporate Governance<strong>AstraZeneca</strong> <strong>Annual</strong> <strong>Report</strong> <strong>and</strong> <strong>Form</strong> <strong>20</strong>-F <strong>Information</strong> <strong>20</strong>11 Corporate Governance <strong>Report</strong> 107