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Symposia and Meetings 2002 Symposia August 29 th -31 st , 2002 Expert meeting „Proteins of the redox metabolism as targets for the development of new drugs against malaria and other protozoan infections“ European Commission COST Action B9 Meeting organizers: Rolf D. Walter, Luise Krauth-Siegel, Eva Liebau, Sylke Müller Chairman of the COST B9 Action: Fred Opperdoes Session 1: Redox metabolism and validation of potential drug targets C.H. Williams (Ann Arbor, USA): “Catalytic mechanism of the high molecular weight thioredoxin reductase” Heiner Schirmer (Heidelberg, Germany): “Glutathione reductase: structure and inhibition” Katja Becker-Brandenburg (Gießen, Germany): “Thioredoxin and glutaredoxin in Plasmodium falciparum” Sylke Müller (Dundee, UK): “Validation of thioredoxin reductase as a drug target in Plasmodium falciparum” Sandra Oza (Dundee, UK): “The synthesis of trypanothione as a potential drug target” Leopold Flohe (Braunschweig, Germany): “Tryparedoxin and tryparedoxin peroxidase” Daniel Dive (Lille, France): “Superoxide dismutase in Plasmodium” Fred Opperdoes (Brussels, Belgium): “Identification of a potential glycosomal ascorbate peroxidase gene in Trypanosoma brucei” Session 2: Detoxification and drug resistance Paul J. Thornalley (Colchester, UK): “The glyoxalase system. Glyoxalase I inhibitors as antitumor (and antimalarial) agents” Luise Krauth-Siegel (Heidelberg, Germany): “The glyoxalase system in trypanosomatids” Eva Liebau (Hamburg, Germany): “Glutathione dependent detoxification processes in Plasmodium” Marc Ouellette (Quebec, Canada). “Drug resistance related to thiol metabolism” Iris Bruchhaus (Hamburg, Germany): “Metronidazole resistance in Entamoeba (including aspects of the redox metabolism in anaerobic protozoa)” Graham Coombs (Glasgow, UK): “The thioredoxin system of Trichomonas vaginalis” Session 3: Target structures, drug design and screening Koen Augustyns (Antwerps, Belgium): “Trypanothione as target in the design of antitrypanosoma and antileishmanial agents” Ken T. Douglas (Manchester, UK): “Design of trypanothione reductase inhibitors” Elisabeth Davioud-Charvet (Lille, France): “Naphthoquinones as inhibitors of trypanothione reductase” Christof Werner (Marburg, Germany): “Structure of the P. falciparum glutamate dehydrogenase” Narimantas Cenas (Vilnius, Littauen): “Antiplasmodial activity of nitroaromatic and quinoidal compounds” C.W. Jefford (Geneva, Switzerland): “Artemisinin and derivatives” 134
November 29 th 2002 Symposium “Klinische Forschung” anläßlich der Verabschiedung von Prof. Dr. Manfred Dietrich, Leiter der Klinischen Abteilung von 1976-2002 • T.M. Fliedner (Universität Ulm): „Knochenmarkversagen und Stammzelle“ • P. Carter (University of North Carolina, Raleigh, USA): „Germfree Biology – basic and clinical research“ • P. Heidt (TNI Institut, Reijswijk, Niederlande): „Gnotobiotic Project Group EORTC – european scientific collaboration“ • R. Arnold (Charité – Universitätsmedizin Berlin): „Knochenmarktransplantation – Infektionsprophylaxe vor 30 Jahren und heute“ • H. Rasche (Zentralkrankenhaus Jürgenstraße, Bremen): „Hämostase und Infektion“ • P. Nawroth (Universität Heidelberg): „Endothelzelle und Infektion“ • P. Kern (Universität Ulm): „Zytokine und Malaria“ • H. Schmitz (BNI): „Zytokine und hämorrhagisches Fieber“ • I. Waase (BNI): „Knochenmark und HIV“ • C. Manegold (BNI): „Hepatitis-Reaktivierung bei HIV“ • M. Vogel (BNI): „Integration von Psychologen im Tropenkrankenhaus“ • R. Bialas (ehem. Präsident der Ärztekammer Hamburg): „Entwicklung und Aufgaben der Ethik-Kommission der Ärztekammer und der Medizinischen Fakultät Hamburg“ • M. Dietrich (BNI): „Malaria Pathophysiologie: Rückblick und Ausblick“ Abschiedsvorlesung von Prof. Dietrich Farewell lecture of Prof. Dietrich 135 Symposia and Meetings
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BERNHARD NOCHT INSTITUTE FOR TROPIC
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Human genetic variants influencing
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Research Funding / Haushaltsmittel
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Introduction The appearance of SARS
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tive project with the Faculty of Me
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since this group headed by Dr. Chri
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Vorwort Das Erscheinen der schweren
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AIDS-Forschung hat eine lange zurü
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europäisches Konsortium mit 8 Part
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Parasitology Section Selected Scien
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Zusammenfassung des Sprechers Die S
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Research Group Clos (Leishmaniasis
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Figure 2: Incidence of ALA in Hué
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jects were assigned to receive dilo
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is increased in the first 24 h of h
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the populations from the endemic ar
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CQR Dd2. In order to determine whet
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Project Description and Results A g
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Project Description and Results Ado
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39 Parasitology Section Figure 2: S
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The paraflagellar rod, a crosshatch
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Figure 1: Suggested in vivo develop
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Medical Microbiology Section Chairm
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Medical Microbiology Section Medica
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Medical Microbiology Section Murine
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Medical Microbiology Section A dry-
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Tropical Medicine Section Selected
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Zusammenfassung des Sektionsspreche
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Kumasi Centre for Collaborative Res
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Data of twin studies and evidence f
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