Research Group Heussler (Malaria I) - Bernhard-Nocht-Institut für ...

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Tropical Medicine Section 2003 saw the Kumasi Centre for Collaborative Research in its 6th year of operation serving as a platform for collaborative scientific projects. At present, 11 research projects are running in parallel. They mainly address topics on malaria, tuberculosis, filariasis and Buruli ulcer. KCCR has staff strength of 30 and comprises up to 130 temporarily employed hospital and field personnel to support the projects. The term was marked by the realization of an ambitious building project funded by the Volkswagen Foundation, the Association of Friends of the Bernhard Nocht Institute, and by German federal and state authorities (see also page 176). In addition to the laboratory and administration block, the new buildings include a lecture and conference room, cafeteria, guesthouse, vehicle workshop, and animal house. These facilities will enable scientists from Ghana and abroad to conduct timely biomedical bench research, working alongside each other in fully equipped laboratories, and to make use of an outstanding infrastructure for epidemiological field studies. Since the inauguration on November 13th 2003, KCCR has established functional laboratory units including microbiology, molecular biology, immunology and virology. The Head of the laboratories, Dr. Berberich, played a pivotal role in organizing the laboratory work and in introducing state-of-the-art technology. KCCR is contributing to the postgraduate programme of Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, by supporting 12 students in their postgraduate training. Two students defended their theses in the Deptartment of Microbiology at the Medical School and in the Department of Biology, Faculty of Science. Two of three PhD students are currently working at the BNITM in Hamburg and at the University of Bonn, and eight Masters students are integrated in KCCR research programmes. Furthermore, six German doctoral students participated in field and laboratory work at KCCR. A seminar series has been started at KCCR and attracted a number of scientists from KNUST. This is seen as an essential tool in upgrading KCCR and KNUST as scientific institutions and naturally contributes to capacity building for Ghana as a whole. Substantial work continued in the KCCR laboratories at Agogo (Malaria, Buruli ulcer), Dunkwa (Onchocerciasis, Buruli ulcer) and Essiama (Elephantiasis). KCCR also works in close collaboration with the Department of Child Health at Komfo Anokye Teaching Hospital, where it participates in the running of a laboratory used for the investigation of severe malaria. The collaboration with the Health Research Unit of Accra, initiated through the project on genetic susceptibility to tuberculosis included support for a laboratory at the Korle-Bu Report on KCCR Activities 88 Teaching Hospital, and this has opened avenues for future fruitful collaborations. We are most grateful to the School of Medical Sciences (SMS), which has hosted KCCR laboratories and offices for six years. Through this close proximity, KCCR became firmly established as part of the university from its early stages. The close relations with SMS continued and were fruitful, resulting in many of the still on-going collaborative projects. The scope of KCCR activities broadened through acquisition of new projects to cover genetics, clinics, diagnostics, therapeutics and ecology of tropical diseases. Various research groups at present are conducting research at KCCR covering: • the genetic background of susceptibility and resistance to malaria and tuberculosis • preventive intermittent treatment of malaria, • chemotherapy and prophylaxis of filariasis, • vaccine candidates in onchocerciasis, • transmission of malaria and filariasis, • diagnostics and environmental studies of Buruli ulcer • HIV seroprevalence among health workers. • health impact of Aflatoxin ingestion Funding for the current KCCR-based research projects is obtained from the European Commission, the German national genome research network (NGFN), the German Malaria Initiative and Volkswagen foundation. Thomas F. Kruppa, Director KCCR Selected KCCR projects are summarized on pp. 70, 80 and 92 of this report.
The KCCR Team and the main laboratory building on the new campus Collaborating Institutions • Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, Ghana • Komfo Anokye Teaching Hospital (KATH), Kumasi, Ghana • Health Research Unit (HRU), Ministry of Health, Accra, Ghana • International Water Management Institute (IWMI), Kumasi, Ghana Investigators and Collaborating Partners • Prof. T. Agbenyega, Dean, SMS • Prof. R. T. Awuah, KNUST • Dr. E.N.L. Browne, KNUST • Dr. O. Darko, KNUST • Dr. W. O. Ellis, KNUST • Dr. W.K. Owiredu, KNUST • Dr. G. K. Amedofu, KNUST • Dr. P. Drechsel, IWMI • Dr. J. O. Gyapong, HRU • Mrs. C. Acheampong, HRU • Dr. N. A. Chinbuah, HRU • Dr. I. Osei, HRU • Dr. U. Irle, Agogo Hospital/Bremen • Dr. M. Evans, St. Georges Hospital, UK • Prof. P. E. Jolly, UAB • Mrs. C. A. Adu, KCCR • Dr. K. O. Kwakye • Prof. Dr. R. Horstmann, BNITM • Prof. Dr. D. W. Büttner, BNITM • Dr. M. Büttner, Hamburg • PD Dr. Norbert Brattig, BNITM • Dr. G. Bretzel, BNITM • Prof.Dr. R. Garms, BNITM • Prof. Dr. A. Hoerauf, BNITM • Prof. Dr. C. G. Meyer, BNITM • Dr. S. Aboagye 89 • Dr. E. Owusu-Dabo • Dr. A. Enimil • Dr. Obeng Baah, KATH • Dr. E. A. Adjei • Dr. A. O. Y. Akoto, KATH • Dr. D. Ansong, KATH • Dr. S. Antwi, KATH • Dr. C. Donkor, KATH • Dr. J. Sylverken, KATH • Dr. A. Owusu Ofori • Dr. B. Nguah • Dr. D. Sambian • Ms. E. Asumeng, KATH • Ms. B. Marbel, HRU • Ms. G. Asamoah • Ms. E. Addo • Ms. V. Owusu, KCCR • Dr. S. Mand, BNITM • Dr. E. Opoku • Dr. E. Yeetey • Dr. Ul. Kriebel, KCCR • Dr. I. Langefeld, BNITM • Dr. R. Kobbe, BNITM • Dr. W Thompson, Agogo Hospital • Dr. Klutse, Dunkwa Hospital • PD Dr. J. May, BNITM • Dr. C. Timman, BNITM • Ms. E. Klinkenberg; IWMI Tropical Medicine Section • Korle-Bu Teaching Hospital, Accra, Ghana • Dunkwa Government Hospital, Ghana • Agogo Presbyterian Hospital, Agogo, Ghana • Eikwe Roman Catholic Hospital, Ghana • St. Georges Hospital Medical School, London • University of Alabama at Birmingham (UAB), USA
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BERNHARD NOCHT INSTITUTE FOR TROPIC
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Human genetic variants influencing
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Research Funding / Haushaltsmittel
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Introduction The appearance of SARS
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tive project with the Faculty of Me
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since this group headed by Dr. Chri
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Vorwort Das Erscheinen der schweren
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AIDS-Forschung hat eine lange zurü
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europäisches Konsortium mit 8 Part
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Parasitology Section Selected Scien
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Zusammenfassung des Sprechers Die S
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Research Group Clos (Leishmaniasis
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Figure 2: Incidence of ALA in Hué
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jects were assigned to receive dilo
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is increased in the first 24 h of h
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the populations from the endemic ar
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CQR Dd2. In order to determine whet
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Staff Activities Staff Activities A
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Staff Activities PD Dr. Joachim Clo
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Staff Activities Editorial Activiti
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Staff Activities Prof. Dr. Rolf Hor
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Staff Activities Prof. Dr. Christia
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Staff Activities Prof. Dr. Egbert T
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Publications Book chapters and Mono
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Publications Herbst R, Ott C, Jacob
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Publications Supali T, Wibowo H, Ru
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Publications Scholze H and Tannich
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Publications Graefe SE, Meyer BS, M
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Publications Schulz A, Mellenthin K
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Appendix 01. Januar 2002 Das BNI wi
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Appendix 01. Oktober 2002 Gemeinsam
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Appendix 01. April 2003 Ergebnis de
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Appendix 01. Juni 2003 Fernsehrepor
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Appendix November 2003 Inauguration
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Appendix red by solar energy could
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Appendix Ansprache von Dr. Thomas F
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Diary 2004/2005 12.-14. November 20
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