Manual of basic techniques for a health laboratory - libdoc.who.int

308 Manual of basic techniques for a health laboratoryFig. 9.81 MacrocytesFig. 9.82 SchistocytesFig. 9.83 SpherocytesFig. 9.84 ElliptocytesSchistocytes (Fig. 9.82)Size: normal or slightly smaller than normal erythrocytes.Fragmented cells.Seen in haemolytic anaemias, sickle-cell disease and thalassaemias.Spherocytes (Fig. 9.83)Size: small (6mm).Shape: perfectly round.Cytoplasm: more darkly stained than normal erythrocytes.Seen in haemolytic anaemias and hereditary spherocytosis.Elliptocytes (Fig. 9.84)Size: normal (8mm).Shape: oval.Cytoplasm: stained darker at the periphery (especially at the poles).