2009_Book_FoodChemistry

78 1 Amino Acids, Peptides, Proteins
Table 1.34. Specificity of proteolytic enzymes [based on cleavage of oxidized B chain of bovine insulin; strong cleavage: ↓, weak cleavage (↓)]
No. a Phe Val Asn Gln His Leu Cys Gly Ser His Leu Val Glu Ala Leu Tyr Leu Val Cys Gly Glu Arg Gly Phe Phe Tyr Thr Pro Lys Ala
Serine peptidases
1 ↓ ↓
2 (↓) ↓ ↓ ↓
3 ↓ ↓ ↓ ↓ (↓) ↓ ↓ ↓ (↓)
4 ↓ ↓ ↓ (↓) ↓ ↓ (↓)
5 ↓ ↓
6 ↓ ↓ ↓ ↓ ↓ ↓
7 (↓) (↓) ↓ ↓ ↓ ↓ ↓ ↓ ↓
8 ↓ ↓ ↓ (↓) ↓ ↓ ↓ ↓ (↓) ↓ ↓
Cysteine peptidases
9 ↓ (↓) (↓) (↓) ↓ (↓) ↓ ↓ ↓ ↓
10 ↓ ↓ ↓ ↓ ↓ ↓
11 ↓ (↓) ↓ ↓ ↓ ↓ ↓ ↓ ↓ (↓) (↓)
Metalopeptidases
12 ↓ ↓ ↓ ↓ ↓ ↓ ↓ ↓ ↓ ↓ ↓
13 ↓ ↓ ↓ ↓ ↓ ↓ ↓ ↓
14 ↓ ↓ ↓ ↓ ↓ ↓ ↓ ↓ ↓ ↓
Aspartic peptidases
15 (↓) (↓) (↓) (↓) ↓ (↓) (↓) (↓) ↓ (↓) ↓ ↓
16 (↓) (↓) ↓ ↓ (↓) ↓ ↓ ↓
17 ↓ ↓ ↓ ↓ ↓
18 ↓ ↓ ↓ ↓ ↓ (↓)
19 (↓) (↓) ↓ ↓ ↓ (↓) ↓ ↓ ↓ ↓
a Enzymes. 7) Endopeptidase from Aspergillus 13) Endopeptidase from Bacillus 19) Endopeptidase from Rhizopus
1) Trypsin (bovine) oryzae subtilis chinensis
2) Chymotrypsin A (bovine) 8) Endopeptidase from Aspergillus 14) Thermolysin (Bacillus
3) Chymotrypsin B (porcine) flavus thermoproteolyticus Rokko)
4) Aspergillopeptidase C 9) Papain (Papaya carica) 15) Pepsin A (porcine)
(Aspergillus oryzae) 10) Ficin III (Ficus glabrata) 16) Renin (calf)
5) Endopeptidase from 11) Chymopapain (Charica papaya) 17) Endopeptidase from Candida
Streptomyces griseus 12) Endopeptidase II from albicans
(trypsin-like) (Aspergillus 18) Endopeptidase from Mucor
6) Subtilisin BPN ′ oryzae) miehei