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474 9 Food Contamination

Table 9.3. Mycotoxins

Fungus/mold Toxin a Toxicity b Effect Occurrence

Claviceps purpurea Ergot alkaloids (I) Ergotism Mainly rye, to a

(gangrenous lesser extent wheat

convulsions)

Aspergillus flavus Aflatoxins (II) 7.2mg/kg Liver cirrhosis, Groundnuts and other

A. parasiticus (rat, orally) liver cancer nuts (almond, Brasil nut)

corn and other cereals,

animal feed, milk

Aspergillus versicolor Sterigmatocystin 120 mg/kg Liver cancer Corn, wheat, animal

A. nidulans (III) (rat, orally) feed

Penicillium expansum Patulin (IV) 35 mg/kg Cellular poison Putrifying fruits,

P. urticae (mouse, orally) fruit juices

Byssochlamis nivea,

B. fulva

Aspergillus ochraceus Ochratoxin A (V) 20 mg/kg Fatty liver and Barley, corn

A. melleus (rat, orally) kidney damage

Fusarium Zearalenone (VI) 0.1mg/kg Estrogen, Corn and other

graminearum (Fusariotoxin F2) over 5 days infertility cereals, animal feed

(swine, orally c )

Fusarium oxysporum Fusariotoxin T2 3.8mg/kg Toxic aleukia, Cereals, animal feed

F. tricinctum (VII) (rat, orally) hemorrhagic

syndrome

Fusarium roseum Deoxynivalenol (VIII) 70 mg/kg Vomiting Cereals, animal feed

F. graminearum (Vomitoxin) (mouse)

Fusarium moniliforme Fumosin FB1 Liver cancer Corn

and FB2 (IX)

a Roman numerals refer to the structural formulas in Fig. 9.1.

b Acute toxicity (LD 50).

c Estrogenic activity.

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