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Pharmaceutical Manufacturing Handbook: Production and

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7.2<br />

NANOTECHNOLOGY IN<br />

PHARMACEUTICAL<br />

MANUFACTURING<br />

Yiguang Jin<br />

Beijing Institute of Radiation Medicine, Beijing, China<br />

Contents<br />

7.2.1<br />

7.2.2<br />

7.2.3<br />

7.2.4<br />

7.2.5<br />

7.2.1<br />

Introduction<br />

Nanomaterials<br />

7.2.2.1 Types of Nanomaterials<br />

7.2.2.2 <strong>Manufacturing</strong> <strong>and</strong> Processing of Nanomaterials<br />

Nanotechnology for Drug Delivery<br />

7.2.3.1 Nanocarriers<br />

7.2.3.2 Nanosuspensions<br />

7.2.3.3 Self - Assembled Drug Nanostructures<br />

Nanomedicine<br />

Perspective<br />

References<br />

INTRODUCTION<br />

Nanotechnology is the ability to produce <strong>and</strong> process nanosized materials or manipulate<br />

objects within the nanoscale. The nanoscale commonly indicates the range<br />

from 1 to 100 nm [1] . However, some scientists regard the nanoscale range from 1<br />

to 200 nm [2] , even to 1000 nm [3] . Making a comparison with a human hair, it is<br />

about 80,000 nm wide. Nanotechnology is a broad, highly interdisciplinary, <strong>and</strong> still<br />

evolving fi eld which involves the production <strong>and</strong> application of physical, chemical,<br />

<strong>and</strong> biological systems. Nanotechnology is likely to have a profound impact on our<br />

economy <strong>and</strong> society in the early twenty - fi rst century, perhaps comparable to that<br />

of information technology or advances in cellular <strong>and</strong> molecular biology. Science<br />

<strong>and</strong> engineering research in nanotechnology promises breakthroughs in areas such<br />

<strong>Pharmaceutical</strong> <strong>Manufacturing</strong> <strong>H<strong>and</strong>book</strong>: <strong>Production</strong> <strong>and</strong> Processes, edited by Shayne Cox Gad<br />

Copyright © 2008 John Wiley & Sons, Inc.<br />

1249

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