Pharmaceutical Manufacturing Handbook: Production and

756 OCULAR DRUG DELIVERY
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33. Grass , G. M. , Wood , R. W. , and Robinson , J. R. ( 1985 ), Effects of calcium chelating agents
on corneal permeability , Invest. Ophthalmol. Vis. Sci. , 26 ( 1 ), 110 – 113 .
34. Liaw , J. , Rojanasakul , Y. , and Robinson , J. R. ( 1992 ), The effect of drug charge type and
charge density on corneal transport , Int. J. Pharm. , 88 ( 1 – 3 ), 111 – 124 .
35. Sieg , J. W. , and Robinson , J. R. ( 1975 ), Vehicle effects on ocular drug bioavailability:
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36. Kaur , I. P. , and Smitha , R. ( 2002 ), Penetration enhancers and ocular bioadhesives: Two
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39. Chrai , S. S. , Patton , T. F. , Mehta , A. , and Robinson , J. R. ( 1973 ), Lacrimal and instilled
fl uid dynamics in rabbit eyes , J. Pharm. Sci. , 62 ( 7 ), 1112 – 1121 .
40. Chrai , S. S. , and Robinson , J. R. ( 1974 ), Ocular evaluation of methylcellulose vehicle in
albino rabbits , J. Pharm. Sci. , 63 ( 8 ), 1218 – 1223 .
41. Sieg , J. W. , and Triplett , J. W. ( 1980 ), Precorneal retention of topically instilled micronized
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42. Lee , V. H. L. , Urrea , P. T. , Smith , R. E. , and Schanzlin , D. J. ( 1985 ), Ocular drug bioavailability
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43. Zimmer , A. , and Kreuter , J. ( 1995 ), Microspheres and nanoparticles used in ocular
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45. Ludwig , A. , and Van Ooteghem , M. ( 1987 ), The infl uence of the osmolality on the precorneal
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46. Kaufman , H. E. , Steinemann , T. L. , Lehman , E. , Thompson , H. W. , Varnell , E. D. ,
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47. Ke , T. - L. , Cagle , G. , Schlech , B. , Lorenzetti , O. J. , and Mattern , J. ( 2001 ), Ocular bioavailability
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48. Meseguer , G. , Buri , P. , Plazonnet , B. , Rozier , A. , and Gurny , R. ( 1996 ), Gamma scintigraphic
comparison of eyedrops containing pilocarpine in healthy volunteers , J. Ocul.
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49. Hui , H. - W. , and Robinson , J. R. ( 1985 ), Ocular delivery of progesterone using a bioadhesive
polymer , Int. J. Pharm. , 26 ( 3 ), 203 – 213 .
50. Lele , B. S. , and Hoffman , A. S. ( 2000 ), Insoluble ionic complexes of polyacrylic acid with
a cationic drug for use as a mucoadhesive, ophthalmic drug delivery system , J. Biomater.
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51. Saettone , M. F. , Giannaccini , B. , Ravecca , S. , La Marca , F. , and Tota , G. ( 1984 ), Polymer
effects on ocular bioavailability — The infl uence of different liquid vehicles on the mydriatic
response of tropicamide in humans and in rabbits , Int. J. Pharm. , 20 ( 1 – 2 ), 187 – 202 .
52. Herrero - Vanrell , R. , Fernandez - Carballido , A. , Frutos , G. , and Cadorniga , R. ( 2000 ),
Enhancement of the mydriatic response to tropicamide by bioadhesive polymers ,
J. Ocul. Pharmacol. Ther. , 16 ( 5 ), 419 – 428 .