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Pharmaceutical Manufacturing Handbook: Production and

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556 BIODEGRADABLE NANOPARTICLES<br />

48. Qi , L. , Xu , Z. , Jiang , X. , Hu , C. , <strong>and</strong> Zou , X. ( 2004 ), Preparation <strong>and</strong> antibacterial activity<br />

of chitosan nanoparticles , Carbohydr. Res. , 339 ( 16 ), 2693 – 2700 .<br />

49. Liu , C. G. , Desai , K. G. , Chen , X. G. , <strong>and</strong> Park , H. J. ( 2005 ), Preparation <strong>and</strong> characterization<br />

of nanoparticles containing trypsin based on hydrophobically modifi ed chitosan ,<br />

J. Agric. Food Chem. , 53 ( 5 ), 1728 – 1733 .<br />

50. Grenha , A. , Seijo , B. , <strong>and</strong> Remunan - Lopez , C. ( 2005 ), Microencapsulated chitosan<br />

nanoparticles for lung protein delivery , Eur. J. Pharm. Sci. , 25 ( 4 – 5 ), 427 – 437 .<br />

51. Enriquez de Salamanca , A. , Diebold , Y. , Calonge , M. , Garcia - Vazquez , C. , Callejo , S. ,<br />

Vila , A. , <strong>and</strong> Alonso , M. J. ( 2006 ), Chitosan nanoparticles as a potential drug delivery<br />

system for the ocular surface: Toxicity, uptake mechanism <strong>and</strong> in vivo tolerance , Invest.<br />

Ophthalmol. Vis. Sci. , 47 ( 4 ), 1416 – 1425 .<br />

52. Saito , H. , Wu , X. , Harris , M. , <strong>and</strong> Hoffman , A. ( 2003 ), Graft copolymers of poly(ethylene<br />

glycol) (PEG) <strong>and</strong> chitosan , Macromol. Rapid Commun. , 18 ( 7 ), 547 – 550 .<br />

53. Bernkop - Schnurch , A. ( 2000 ), Chitosan <strong>and</strong> its derivatives: Potential excipients for<br />

peroral peptide delivery systems , Int. J. Pharm. , 194 ( 1 ), 1 – 13 .<br />

54. Hyung Park , J. , Kwon , S. , Lee , M. , Chung , H. , Kim , J. H. , Kim , Y. S. , Park , R. W. , Kim , I.<br />

S. , Bong Seo , S. , Kwon , I. C. , <strong>and</strong> Young Jeong , S. ( 2006 ), Self - assembled nanoparticles<br />

based on glycol chitosan bearing hydrophobic moieties as carriers for doxorubicin: In<br />

vivo biodistribution <strong>and</strong> anti - tumor activity , Biomaterials , 27 ( 1 ), 119 – 126 .<br />

55. Mansouri , S. , Cuie , Y. , Winnik , F. , Shi , Q. , Lavigne , P. , Benderdour , M. , Beaumont , E. ,<br />

<strong>and</strong> Fern<strong>and</strong>es , J. C. ( 2006 ), Characterization of folate - chitosan - DNA nanoparticles for<br />

gene therapy , Biomaterials , 27 ( 9 ), 2060 – 2065 .<br />

56. Yan , C. , Chen , D. , Gu , J. , <strong>and</strong> Qin , J. ( 2006 ), Nanoparticles of 5 - fl uorouracil (5 - FU)<br />

loaded N - succinyl - chitosan (Suc - Chi) for cancer chemotherapy: Preparation, characterization<br />

— in - vitro drug release <strong>and</strong> anti - tumour activity , J. Pharm. Pharmacol. , 58 ( 9 ),<br />

1177 – 1181 .<br />

57. Park , J. S. , Han , T. H. , Lee , K. Y. , Han , S. S. , Hwang , J. J. , Moon , D. H. , Kim , S. Y. , <strong>and</strong><br />

Cho , Y. W. ( 2006 ), N - acetyl histidine - conjugated glycol chitosan self - assembled nanoparticles<br />

for intracytoplasmic delivery of drugs: Endocytosis, exocytosis <strong>and</strong> drug release ,<br />

J. Controlled Release. , 115 ( 1 ), 37 – 45 .<br />

58. V<strong>and</strong>ervoort , J. , <strong>and</strong> Ludwig , A. ( 2004 ), Preparation <strong>and</strong> evaluation of drug - loaded<br />

gelatin nanoparticles for topical ophthalmic use , Eur. J. Pharm. Biopharm. , 57 ( 2 ),<br />

251 – 261 .<br />

59. Cascone , M. G. , Lazzeri , L. , Carmignani , C. , <strong>and</strong> Zhu , Z. ( 2002 ), Gelatin nanoparticles<br />

produced by a simple W/O emulsion as delivery system for methotrexate , J. Mater. Sci.<br />

Mater. Med. , 13 ( 5 ), 523 – 526 .<br />

60. Lu , Z. , Yeh , T. K. , Tsai , M. , Au , J. L. , <strong>and</strong> Wientjes , M. G. ( 2004 ), Paclitaxel - loaded gelatin<br />

nanoparticles for intravesical bladder cancer therapy , Clin. Cancer Res. , 10 ( 22 ),<br />

7677 – 7684 .<br />

61. Bajpai , A. K. , <strong>and</strong> Choubey , J. ( 2006 ), Design of gelatin nanoparticles as swelling<br />

controlled delivery system for chloroquine phosphate , J. Mater. Sci. Mater. Med. , 17 ( 4 ),<br />

345 – 358 .<br />

62. Li , J. K. , Wang , N. , <strong>and</strong> Wu , X. S. ( 1997 ), A novel biodegradable system based on gelatin<br />

nanoparticles <strong>and</strong> poly(lactic -co - glycolic acid) microspheres for protein <strong>and</strong> peptide<br />

drug delivery , J. Pharm. Sci. , 86 ( 8 ), 891 – 895 .<br />

63. Farrugia , C. A. , <strong>and</strong> Groves , M. J. ( 1999 ), The activity of unloaded gelatin nanoparticles<br />

on murine melanoma B16 - F0 growth in vivo , Anticancer Res. , 19 ( 2A ), 1027 – 1031 .<br />

64. Coester , C. , Kreuter , J. , von Briesen , H. , <strong>and</strong> Langer , K. ( 2000 ), Preparation of avidin -<br />

labelled gelatin nanoparticles as carriers for biotinylated peptide nucleic acid (PNA) ,<br />

Int. J. Pharm. , 196 ( 2 ), 147 – 149 .

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