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Pharmaceutical Manufacturing Handbook: Production and

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762 OCULAR DRUG DELIVERY<br />

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148. Saettone , M. F. , Giannaccini , B. , Chetoni , P. , Galli , G. , <strong>and</strong> Chiellini , E. ( 1984 ), Vehicle<br />

effects in ophthalmic bioavailability: An evaluation of polymeric inserts containing<br />

pilocarpine , J. Pharm. Pharmacol. , 36 ( 4 ), 229 – 234 .<br />

149. Saettone , M. F. , Torracca , M. T. , Pagano , A. , Giannaccini , B. , Rodriguez , L. , <strong>and</strong> Cini , M.<br />

( 1992 ), Controlled release of pilocarpine from coated polymeric ophthalmic inserts<br />

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150. Saettone , M. F. , Chetoni , P. , Bianchi , L. M. , Giannaccini , B. , Conte , U. , <strong>and</strong> Sangalli , M.<br />

E. ( 1995 ), Controlled release of timolol maleate from coated ophthalmic mini - tablets<br />

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151. Sasaki , H. , Tei , C. , Nishida , K. , <strong>and</strong> Nakamura , J. ( 1993 ), Drug release from an ophthalmic<br />

insert of a beta - blocker as an ocular drug delivery system , J. Controlled Release , 27 ( 2 ),<br />

127 – 137 .<br />

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oxacin hydrochloride from different polymer formulations: In vitro <strong>and</strong> in vivo studies ,<br />

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154. Pijls , R. T. , Sonderkamp , T. , Daube , G. W. , Krebber , R. , Hanssen , H. H. L. , Nuijts , R. M.<br />

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155. Lux , A. , Maier , S. , Dinslage , S. , Suverkrup , R. , <strong>and</strong> Diestelhorst , M. ( 2003 ), A comparative<br />

bioavailability study of three conventional eye drops versus a single lyophilisate , Br. J.<br />

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156. Dinslage , S. , Diestelhorst , M. , Weichselbaum , A. , <strong>and</strong> Suverkrup , R. ( 2002 ), Lyophilisates<br />

for drug delivery in Ophthalmology: Pharmacokinetics of fl uorescein in the human<br />

anterior segment , Br. J. Ophthalmol. , 86 ( 10 ), 1114 – 1117 .<br />

157. Ceulemans , J. , Vermeire , A. , Adriaens , E. , Remon , J. P. , <strong>and</strong> Ludwig , A. ( 2001 ), Evaluation<br />

of a mucoadhesive tablet for ocular use , J. Controlled Release , 77 ( 3 ), 333 – 344 .

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