4. Hrvatski kongres kliniËke citologije 4th Croatian Congress ... - Penta
4. Hrvatski kongres kliniËke citologije 4th Croatian Congress ... - Penta
4. Hrvatski kongres kliniËke citologije 4th Croatian Congress ... - Penta
Create successful ePaper yourself
Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.
<strong>4.</strong> <strong>Hrvatski</strong> <strong>kongres</strong> <strong>kliniËke</strong> <strong>citologije</strong> / 1. <strong>Hrvatski</strong> simpozij analitiËke <strong>citologije</strong> / 2. <strong>Hrvatski</strong> simpozij citotehnologije<br />
102<br />
Klinička citologija - Usmena predavanja<br />
MORPHOMETRY OF TUMOUR CELLS IN DIFFERENT GRADES AND TYPES<br />
OF BREAST CANCER<br />
Prvulović I1 , Kardum-Skelin I2 , Jakić-Razumović J3 , Manojlović S4 1General Hospital Slavonski Brod, Department of Cytology, Slavonski Brod, Croatia<br />
2Merkur University Hospital, Laboratory of Cytology and Hematology, Zagreb, Croatia<br />
3Clinical Hospital Centre Zagreb, Department of Pathology, Zagreb, Croatia<br />
4Dubrava University Hospital, Department of Pathology, Zagreb, Croatia<br />
Objective. To compare morphometric features between different types and grades of<br />
breast cancer. Methods. Morphometric analysis was performed using the Sform (Vamstec,<br />
Zagreb) software on the May-Grunwald-Giemsa stained fine needle aspiration cytology<br />
specimens of breast tissue. Selected specimens represented all breast smears in<br />
Clinical Hopsital Merkur from 2001 to 2005, malignant on cytological report and histologicaly<br />
confirmed. Investigated group consisted of 42 patients. The following features were<br />
investigated: area, outline, maximum radius, minimum radius, convex area, breadth,<br />
length, nucelar/cytoplasmatic ratio, form factor and elongation. Statistic 7.1 and chi2-<br />
test were used. Results. Morphometric analysis showed statistically significant differences<br />
between all investigated groups. Conclusion. Morphometric features considered<br />
individually were highly associated with type and grade of breast tumour.<br />
ivanahodak@yahoo.com<br />
LYMPHOMATOID GRANULOMATOSIS IN A 23-YEAR-OLD MAN- CYTOLOGICAL AND<br />
HYSTOLOGICAL TYPING AND RAPID RESPONSE TO STEROID AND CYCLOPHOSPHAMIDE<br />
Rakušić N1 , Krmpotić D1 , Hećimović A1 , Boras Z1 , Vrabec-Branica B1 , Džebro S2 ,<br />
Rakušić N3 , Rešković T4 1University Hospital for Lung Diseases „Jordanovac“, Zagreb, Croatia<br />
2Department of Pathology, Clical Hospital „Merkur“, Zagreb, Croatia<br />
3Medical School University of Rijeka, Croatia<br />
4Medical School University of Zagreb, Croatia<br />
Lymphomatoid granulomatosis (LG) is currently called as extranodal angiocentric and<br />
angiodestructive immunoproliferative lesion with various degree of histological diferentiation<br />
and clinical agression. Histological grading and clinical manifestations are<br />
due to number of atypical large EBV+ B-lymphatic cells. We report case of 23-years old<br />
man, clinicaly presented with fever, sweating, and physical intolerance, and with bilateral<br />
pulmonary infiltrates of nodular type and destructive changes on the chest x-ray,<br />
previously treated with antituberculotics for 1,5 months. As the disease showed progression,<br />
diagnostic procedures extended to transbroncial lung biopsy and percutaneous<br />
fine needle aspiration with cytologic and histologic analysis of colected speciemens, all<br />
being not enough conclusive. LG was confirmed by open lung biopsy, followed by induction<br />
of corticosteroids and cyclophosphamide therapy. Very good clinical, functional and<br />
radiomorphologic improvement was achieved in a few weekls and remission of diseases<br />
maintanined in long term follow-up.<br />
neven.rakusic@zg.t-com.hr