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4. Hrvatski kongres kliniËke citologije 4th Croatian Congress ... - Penta

4. Hrvatski kongres kliniËke citologije 4th Croatian Congress ... - Penta

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Clinical Cytology - Posters<br />

FINE-NEEDLE ASPIIRATION CYTOLOGY OF APOCRINE HIDRADENOMA<br />

Novak NP1 , Kaić G1 , Tomasović-Lončarić Č2 , Žic R3 , Škoro M1 , Trutin Ostović K1 1Dubrava University Hospital, Department of Clinical Cytology and Cytometry, Zagreb, Croatia<br />

2Dubrava University Hospital, Department of Pathology, Zagreb, Croatia<br />

3Dubrava University Hospital, Department of Plastic, Reconstructive and Aesthetic<br />

Surgery, Zagreb, Croatia<br />

An apocrine hidradenoma is a benign adnexal neoplasm, usually covered by intact skin,<br />

but may show superficial ulceration and serous discharge. This feature is raising the<br />

possibility of malignancy as it was in our case of macroscopically suspicious tumor. We<br />

described cytomorphologic features of cutaneous nodule that might be a lead to the cytologic<br />

diagnosis of hidradenoma, but primary or secondary malignant tumor has been<br />

ruled out first.<br />

dr.nina.novak@gmail.com<br />

FINE NEEDLE ASPIRATION BIOPSY OF FOLLICULAR THYROID TUMORS<br />

Pauzar B, Staklenac B, Lončar B<br />

Department of Clinical Cytology, Clinical Hospital Osijek, Croatia<br />

US-guided fine needle aspiration cytology is currently the best diagnostic tool for thyroid<br />

nodules. However, it is not sensitive and specific enough for discriminating between<br />

benign and malignant follicular tumors. The aim of this research is to make a detailed<br />

and objective determination of the morphological characteristics of cells in cytological<br />

smears of aspirated material of pathohistologically verified follicular and Hürthle adenomas<br />

and carcinoma. The research included 62 patients with cytologically diagnosed<br />

follicular or Hürthle cell tumors, and 15 patients with hyperplastic nodules. Echographic<br />

findings are divided into three groups: isoechogenic, hypoechogenic and hyperechogenic<br />

nodules. The nodules are classified by size according to the WHO pT classification.<br />

The semiquantitative analysis determined the frequency of particular morphological<br />

elements in the cytological smear. We analyzed the cellularity of the smear, cohesion<br />

between follicular cells, acinar formations, bare nuclei, characteristics of the nucleus<br />

and the cytoplasm, and the presence of colloid. The statistical analysis of cytological<br />

parameters has indicated that none of the cytological parameters alone is discriminating<br />

enough between non-tumor and tumor changes, or benign and malignant follicular<br />

thyroid nodules. The analysis of age, sex, nodule size and ultrasound findings has not<br />

shown the correlation between any of these parameters with the malignant or benign<br />

follicular tumors. The cytological analysis of the smears for patients with follicular tumors,<br />

in combination with clinical data and other diagnostic methods, contributes to<br />

more precise diagnostics, but is not sufficient for the discrimination between benign and<br />

malignant follicular tumors.<br />

pauzar.biljana@kbo.hr<br />

135<br />

4 th <strong>Croatian</strong> <strong>Congress</strong> of Clinical Cytology / 1 st <strong>Croatian</strong> Symposium of Analytical Cytology / 2 nd <strong>Croatian</strong> Symposium of Cytotechnology

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