4. Hrvatski kongres kliniËke citologije 4th Croatian Congress ... - Penta

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4. Hrvatski kongres kliniËke citologije / 1. Hrvatski simpozij analitiËke citologije / 2. Hrvatski simpozij citotehnologije 104 Klinička citologija - Usmena predavanja VILLOGLANDULAR PAPILLARY ADENOCARCINOMA OF THE UTERINE CERVIX WITH AGGRESSIVE CLINICAL COURSE - A CASE REPORT Rubeša-Mihaljević R1 , Vrdoljak-Mozetič D1 , Verša Ostojić D1 , Štemberger-Papić S1 , Sindik N2 , Krašević M3 1 Department of Gynecological Cytology, University Department of Gynecology and Obstetrics, University Hospital Center Rijeka, Rijeka, Croatia 2University Department of Gynecology and Obstetrics, University Hospital Center Rijeka, Rijeka, Croatia 3 Department of Pathology, Rijeka University School of Medicine, Rijeka, Croatia Aim of the study: Villoglandular papillary adenocarcinoma (VGA) of cervix is an uncommon but well recognized histologic subtype of cervical adenocarcinoma which usually affects young women. Based on the favorable outcomes reported in most of previous cases the tumor is generally considered to have an indolent clinical course with excellent prognosis. We present a case of a 22-year-old woman admitted for glandular abnormality on cervical smear and episodes of vaginal bleeding. In the Pap smear, the cytologic features were suspicious but not diagnostic of adenocarcinoma, therefore reported as atypical glandular cells (AGC). Histological examination confirmed VGA associated with lymphovascular space invasion. The patient underwent radical operative procedure. Intraoperative cytologic examination detected pelvic lymph nodes metastasis. The patient was confirmed to be in an advanced stage - III B (FIGO). During a two years follow-up period a rapid dissemination of the tumor occurred and resulted with a fatal outcome. Conclusion: Although VGA has been reported to have a favorable prognosis, several cases with lymph node involvement have already been described. Cervical smears examination would be helpful for an early diagnosis of VGA, however the cytologic recognition is often difficult. Further investigation of the pathogenesis, diagnosis and therapy of the tumor is needed. roberta.rubesa@gmail.com
Clinical Cytology - Oral Presentations ADDITIONAL CYTOMORPHOLOGICAL CRITERIA IN DIAGNOSIS OF PILOMATRICOMA - BENIGN TUMOR WITH BAD REPUTATION Seili-Bekafigo I1 , Jonjić N2 , Štemberger C1 , Rajković-Molek K1 1 KBC Rijeka, Department of Cytology, Department.of Internal Medicine, Rijeka, Croatia 2 Rijeka University School of Medicine, Department of Pathology, Rijeka, Croatia Aim. Pilomatricomas (PM) are benign skin appendageal tumors,with differentiation towards hair-forming cells,usually found in children. They are frequently misdiagnosed by clinicians, and there are many reports of false positive diagnoses made on fine needle aspirates (FNA). PM are often mistaken for «small round cell tumors in children, or for Merkel cell carcinoma, basalioma and metastatic small cell carcinoma in adults, with possible over-aggressive therapeutic approach. The aim of this study was to confirm existing and possibly add some new morphologic and morphometric characteristics of PM. Patients and methods. In 6 cases of PM, correctly diagnosed preoperatively by FNA, clinical, cytomorphologic and basic morphometric features (the longest nuclear diameter), were analyzed, and compared with 4 cases of malignant tumors with similar clinical presentation. Smears were stained according to May-Gruenwald-Giemsa (MGG) method. Results. Morphometric data did not prove to be helpful. In addition to well known cytomorphologic characteristics of PM, in all 6 cases we found basophilic cytoplasmatic protrusions, that could be useful additional cytomorphologic feature of PM. Conclusion. We concluded that cytomorphologic characteristics of PM are reliable enough for correct preoperative diagnosis in adequate specimens. The best results are achieved when FNA is performed by an experienced cytologist, considering all relevant clinical data. irena.seili-bekafigo@ri.t-com.hr 105 4 th Croatian Congress of Clinical Cytology / 1 st Croatian Symposium of Analytical Cytology / 2 nd Croatian Symposium of Cytotechnology
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Final programme and abstract book
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UTORAK, 13.10.2009. SRIJEDA, 14.10.
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4. Hrvatski kongres kliniËke citologije 4th Croatian Congress ... - Penta

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