4. Hrvatski kongres kliniËke citologije 4th Croatian Congress ... - Penta

Recommendations

Info

4. Hrvatski kongres kliniËke citologije / 1. Hrvatski simpozij analitiËke citologije / 2. Hrvatski simpozij citotehnologije ALLELE FREQUENCIES OF FIVE X-LINKED MICROSATELLITES IN THE CROATIAN POPULATION AND THEIR APPLICATION IN PRENATAL DIAGNOSIS OF SEX CHROMOSOME ANEUPLOIDIES Crkvenac Gornik K1 , Štingl K2 , Grubić Z2 , Tonković Đurišević I1 , Huljev Frković S1 , Begović D1 1 Division of Genetics and Metabolism, Clinic of Paediatrics 2 Tissue Typing Centre, University Hospital Centre, Zagreb, Croatia Five STR loci located on the X chromosome (DXS9895, GATA172D05, DXS6810, DXS6803 and HPRTB) were investigated in the group of 183 unrelated healthy individuals from Croatia (90 males and 93 females). No deviation from the Hardy-Weinberg equilibrium could be detected while allele frequencies showed similar distribution in male and female samples. All investigated loci with the exception of DXS6810 locus have demonstrated sufficient polymorphism to be considered valuable in prenatal diagnosis of sex chromosome aneuploidies. The DXS6810 locus showed low polymorphism with only 6 observed alleles and polymorphism information content (PIC) value lower than 0.75. The analysis of these five STR loci was also performed on the samples from 13 patients with X chromosome disorders (Turner Syndrome - 6 cases; Klinefelter Syndrome - 5 cases and Triplo X Syndrome - 2 cases). The comparison of results obtained by the analysis of STR loci with the results from the standard cytogenetic methods did not reveal any discrepancies. The present data therefore confirm the diagnostic value of investigated X-STR loci for the prenatal detection of chromosome X numerical disorders. kcrkven@kbc-zagreb.hr 162 Analitička citologija - Posteri
Analytical Cytology - Posters EXPRESSION OF P53, BCL-2, SURVIVIN AND AKT-1 IN PERIPHERAL BLOOD, BONE MARROW AND LYMPH NODES IN B-CLL Gizdić B1 , Miletić Z1 , Štoos Veić T1 , Pandžić Jakšić V1 , Martinović M1 , Kušeć R1 , Jakšić B2 , Pejša V1 , Trutin Ostović K1 , Jakšić O1 1 Dubrava University Hospital, Zagreb, Croatia 2 Merkur University Hospital, Zagreb, Croatia Aims.We examined expression of several key factors regulating proliferation and apoptosis in B-CLL and difference in expression between them in peripheral blood (PB), bone marrow (BM) and lymph nodes (LN) representing major compartments in B-CLL. Methods. Samples from 25 B-CLL patients were taken by conventional techniques from PB, BM and LN. We analyzed CD5+CD19+ cells for expression of survivin, p53, bcl-2, Akt-1 and Ki-67 using flow cytometry and expressed results as mean fluorescence intensity (MFI). Results were statistically analyzed by pair tests. Results. Mean age of analyzed patients was 69 years (56% male). Mean b-2 microglobulin was 4.65 mg, mean TTM 9.76. There were 10, 10 and 5 patients in Binet stages A, B and C respectively. Median expressions (MFI) for PB, BM and LN respectively were: survivin 1.44, 1.19 and 2.15 (p
Page 1:
4. Hrvatski kongres kliniËke citol
Page 4 and 5:
Page 6 and 7:
Page 8 and 9:
Page 10 and 11:
Page 13 and 14:
Final programme and abstract book
Page 15:
UTORAK, 13.10.2009. SRIJEDA, 14.10.
Page 18 and 19:
Page 20 and 21:
Page 22 and 23:
Page 24 and 25:
Page 26 and 27:
Page 28 and 29:
Page 30 and 31:
Page 32 and 33:
Page 34 and 35:
Page 36 and 37:
Page 38 and 39:
Page 40 and 41:
Page 42 and 43:
Page 44 and 45:
Page 46 and 47:
Page 48 and 49:
Page 50 and 51:
Page 52 and 53:
Page 54 and 55:
Page 56 and 57:
Page 58 and 59:
Page 60 and 61:
Page 62 and 63:
Page 64 and 65:
Page 66 and 67:
Page 68 and 69:
Page 70 and 71:
Page 72 and 73:
Page 74 and 75:
Page 76 and 77:
Page 78 and 79:
Page 80 and 81:
Page 82 and 83:
Page 84 and 85:
Page 86 and 87:
Page 88 and 89:
Page 90 and 91:
Page 92 and 93:
Page 94 and 95:
Page 96 and 97:
Page 98 and 99:
Page 100 and 101:
Page 102 and 103:
Page 104 and 105:
Page 106 and 107:
Page 108 and 109:
Page 110 and 111:
Page 112 and 113:
Page 114 and 115: 4. Hrvatski kongres kliniËke citol
Page 194: 4. Hrvatski kongres kliniËke citol
show all

4. Hrvatski kongres kliniËke citologije 4th Croatian Congress ... - Penta

Create successful ePaper yourself

Delete template?

Save as template?