4. Hrvatski kongres kliniËke citologije 4th Croatian Congress ... - Penta
4. Hrvatski kongres kliniËke citologije 4th Croatian Congress ... - Penta
4. Hrvatski kongres kliniËke citologije 4th Croatian Congress ... - Penta
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<strong>4.</strong> <strong>Hrvatski</strong> <strong>kongres</strong> <strong>kliniËke</strong> <strong>citologije</strong> / 1. <strong>Hrvatski</strong> simpozij analitiËke <strong>citologije</strong> / 2. <strong>Hrvatski</strong> simpozij citotehnologije<br />
ABDOMINAL NON-EPITHELIAL TUMORS DIAGNOSED BY FINE NEEDLE<br />
ASPIRATION CYTOLOGY<br />
Škegro D1 , Obad-Kovačević D1 , Škurla B1 , Mrzljak A1 , Filipec-Kanižaj T1 ,<br />
Vidić-Paulišić I2 , Jelić-Puškarić B1 1 University Hospital Merkur, Zagreb, Croatia<br />
2 County Hospital Čakovec, Čakovec, Croatia<br />
138<br />
Klinička citologija - Posteri<br />
Non-epithelial tumor in abdominal cavity is less frequent finding than epithelial tumor<br />
regardless of site or primary or metastatic origin. Abdominal palpation discovers tumor<br />
mass occasionally; therefore visualization is possible by using imaging technologies.<br />
Ultrasound (US) and computed tomography (CT) enables precise localization and tissue<br />
sampling by fine needle aspiration (FNA) for cytology analysis and additional diagnostic<br />
technologies. Material and methods: Data of 761 FNA of intraabdominal mass performed<br />
with CHIBA needle in last 10 years were analyzed. Tumor mass suitable for FNA were<br />
punctured in liver (335), pancreas (124), spleen (32) kidney (21), adrenal gland (7) and<br />
retroperitoneal and mesenterial lymph nodes (242). Smears were stained according<br />
to May-Grünwald-Giemsa and according to cytochemistry and immunocytochemistry<br />
methods. For differentiation of malignant lymphomas flow-cytometry immunofenotypisation,<br />
cytogenetic and/or molecular analysis (PCR) were additionally performed.<br />
Results: Out of total of 761 specimens malignant tumor was diagnosed in 532 (70%). Nonepithelial<br />
tumor was diagnosed in 154 (20%) - 21 sarcoma, 6 melanoma, 7 embriogenic<br />
tumors and 120 malignant lymphomas. Subtypes of sarcoma were determined based on<br />
cytomorphology and immunocytochemistry - 4 gastrointestinal stromal tumor (GIST), 3<br />
liposarcoma, 2 rhabdomysarcoma, 2 leiomyosarcoma, 2 angiosarcoma, 1 fibrosarcoma<br />
and 7 samples were without subtype.<br />
Conclusion: US or CT guided FNA of abdominal tumor mass followed by cytoanalysis<br />
(cytochemistry and immunocytochemistry methods, flow-cytometry immunofenotypisation,<br />
cytogenetic and/or molecular analysis) is trustworthy diagnostic procedure for<br />
distinguishing non-epithelial from epithelial tumor and moreover for subtypisation of<br />
non-epithelial tumors.<br />
dinko.skegro@kb-merkur.hr