4. Hrvatski kongres kliniËke citologije 4th Croatian Congress ... - Penta

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4. Hrvatski kongres kliniËke citologije / 1. Hrvatski simpozij analitiËke citologije / 2. Hrvatski simpozij citotehnologije 102 Klinička citologija - Usmena predavanja MORPHOMETRY OF TUMOUR CELLS IN DIFFERENT GRADES AND TYPES OF BREAST CANCER Prvulović I1 , Kardum-Skelin I2 , Jakić-Razumović J3 , Manojlović S4 1General Hospital Slavonski Brod, Department of Cytology, Slavonski Brod, Croatia 2Merkur University Hospital, Laboratory of Cytology and Hematology, Zagreb, Croatia 3Clinical Hospital Centre Zagreb, Department of Pathology, Zagreb, Croatia 4Dubrava University Hospital, Department of Pathology, Zagreb, Croatia Objective. To compare morphometric features between different types and grades of breast cancer. Methods. Morphometric analysis was performed using the Sform (Vamstec, Zagreb) software on the May-Grunwald-Giemsa stained fine needle aspiration cytology specimens of breast tissue. Selected specimens represented all breast smears in Clinical Hopsital Merkur from 2001 to 2005, malignant on cytological report and histologicaly confirmed. Investigated group consisted of 42 patients. The following features were investigated: area, outline, maximum radius, minimum radius, convex area, breadth, length, nucelar/cytoplasmatic ratio, form factor and elongation. Statistic 7.1 and chi2- test were used. Results. Morphometric analysis showed statistically significant differences between all investigated groups. Conclusion. Morphometric features considered individually were highly associated with type and grade of breast tumour. ivanahodak@yahoo.com LYMPHOMATOID GRANULOMATOSIS IN A 23-YEAR-OLD MAN- CYTOLOGICAL AND HYSTOLOGICAL TYPING AND RAPID RESPONSE TO STEROID AND CYCLOPHOSPHAMIDE Rakušić N1 , Krmpotić D1 , Hećimović A1 , Boras Z1 , Vrabec-Branica B1 , Džebro S2 , Rakušić N3 , Rešković T4 1University Hospital for Lung Diseases „Jordanovac“, Zagreb, Croatia 2Department of Pathology, Clical Hospital „Merkur“, Zagreb, Croatia 3Medical School University of Rijeka, Croatia 4Medical School University of Zagreb, Croatia Lymphomatoid granulomatosis (LG) is currently called as extranodal angiocentric and angiodestructive immunoproliferative lesion with various degree of histological diferentiation and clinical agression. Histological grading and clinical manifestations are due to number of atypical large EBV+ B-lymphatic cells. We report case of 23-years old man, clinicaly presented with fever, sweating, and physical intolerance, and with bilateral pulmonary infiltrates of nodular type and destructive changes on the chest x-ray, previously treated with antituberculotics for 1,5 months. As the disease showed progression, diagnostic procedures extended to transbroncial lung biopsy and percutaneous fine needle aspiration with cytologic and histologic analysis of colected speciemens, all being not enough conclusive. LG was confirmed by open lung biopsy, followed by induction of corticosteroids and cyclophosphamide therapy. Very good clinical, functional and radiomorphologic improvement was achieved in a few weekls and remission of diseases maintanined in long term follow-up. neven.rakusic@zg.t-com.hr
Clinical Cytology - Oral Presentations FINE NEEDLE ASPIRATION CYTOLOGY IN DIAGNOSING RARE BREAST CARCINOMA-TWO CASE REPORTS Ramljak V1 , Šarčević B2 , Vrdoljak DV3 , Bobuš Kelčec I1 , Agai M1 , Trutin Ostović K4 1 University Hospital for Tumors, Department of Cytology, Zagreb, Croatia 2 University Hospital for Tumors, Department of Pathology, Zagreb, Croatia 3 University Hospital for Tumors Department of Surgical Oncology, Zagreb, Croatia 4Dubrava University Hospital., Department of Clinical Cytology and Cytometry, Zagreb, Croatia In this paper, we are presenting the two cases of very rare tumors: breast sebaceous carcinoma, which has been described for the first time in Croatian medical literature, and pure breast squamous carcinoma. First case, sebaceous carcinoma, is still quite unknown regarding its morphological characteristics and biological behavior. In the second case, squamous carcinoma, also very rare, was found in a patient who previously had a number of diagnosed head and neck skin carcinomas, and was diagnosed as primary squamous breast carcinoma. As a first case we present a 85-year-old female with a two months history of swelling of the left breast under the mammilla. The second one, a 69-year-old female presented to our hospital in January 2008 with a two months history of a lump in the lower outer region of the left breast and enlarged lymph nodes in left axillary region. Fine needle aspiration cytology (FNAC) of the breast was performed in order to diagnose the exact type of both tumours. This methodology was found important in diagnosis, but in both cases showed certain limitations in diagnosing such rare tumors. The final diagnoses were determined after carefully synthesizing the histological findings and clinical data. Careful and accurate classification of these tumors is necessary. A detailed analysis of their biological behavior and response to the therapy is necessary in order to formulate definite recommendations in managing these patients/diseases. vesna.ramljak@kzt.hr 103 4 th Croatian Congress of Clinical Cytology / 1 st Croatian Symposium of Analytical Cytology / 2 nd Croatian Symposium of Cytotechnology
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Final programme and abstract book
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UTORAK, 13.10.2009. SRIJEDA, 14.10.
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4. Hrvatski kongres kliniËke citologije 4th Croatian Congress ... - Penta

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