4. Hrvatski kongres kliniËke citologije 4th Croatian Congress ... - Penta

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4. Hrvatski kongres kliniËke citologije / 1. Hrvatski simpozij analitiËke citologije / 2. Hrvatski simpozij citotehnologije 118 Klinička citologija - Posteri ADENOMATOID NODULES AND SUSPICIOUS FOLLICULAR LESIONS OF THE THYROID OBTAINED BY FINE NEEDLE ASPIRATION CYTOLOGY Dabelić N1 , Mateša N1 , Mateša-Anić D2 , Kusić Z1 1Department of Oncology and Nuclear Medicine, Sisters of Charity University Hospital, Zagreb, Croatia 2 Department of Otorhinolaryngology, Special Hospital for Medical Rehabilitation “Thalassotherapia”, Crikvenica, Croatia Aim: to assess malignancy risk in adenomatoid nodules and suspicious follicular lesions of the thyroid obtained by fine needle aspiration (FNA) cytology. Methods: retrospective research of 276 patients (pts) who underwent thyroid surgery after preoperative ultrasound-guided FNA diagnosis of adenomatoid nodule, cellular follicular lesion, “suspicious for follicular neoplasm” or follicular neoplasm. Results: Out of 276 pts, FNA reports showed 15 diagnoses (5%) of adenomatoid nodules, 73 (26%) cellular follicular lesions, 76 (28%) “suspicious for follicular neoplasm”, and 112 diagnoses (41%) of follicular neoplasm. FNA reports were compared with pathohistological findings. In FNA reports of adenomatoid nodule, there were 7 (47%) pathohistological diagnoses (PHDs) of nodular goiter, and 8 (53%) PHDs of follicular adenoma. In FNA reports of cellular follicular lesion,, there were 2 (3%) PHDs of thyroiditis, 32 (44%) PHDs of nodular goiter, 38 (52%) PHDs of follicular adenoma, and 1 (1%) PHD of papillary carcinoma. In FNA reports of “suspicious for follicular neoplasm), there was 1 (1%) PHD of thyroiditis, 24 (32%) PHDs of nodular goiter, 47 (62%) PHDs of follicular adenoma and 4 (5%) diagnoses of papillary carcinoma. In FNA reports of follicular neoplasm, there were 25 (22%) PHDs of nodular goiter, 72 (64%) PHDs of follicular adenoma, and 15 (14%) PHDs of thyroid carcinoma. We found significant difference (p
Clinical Cytology - Posters THE ROLE OF CYTOLOGY IN THE DIAGNOSIS OF PYELON TUMOUR - A CASE REPORT Ezgeta Karačić D1 , Valetić J2 , Zeljko Ž3 , Vidas Ž3 , Jelić-Puškarić B4 , Sabljar-Matovinović M5 , Kardum-Skelin I4 1 Vukovar General Hospital, Department of Cytology, Vukovar, Croatia 2 University Hospital Merkur, Department of Gynaecology & Obstetrics, Zagreb, Croatia 3 University Hospital Merkur, Division of Urology, Zagreb, Croatia 4University Hospital Merkur, Department of Medicine, Laboratory for Cytology and Hematology, Zagreb, Croatia 5 University Hospital Merkur, Department of Medicine, Zagreb, Croatia Tumours of the renal pelvis and ureter arising from epithelial and mesenchymal elements account for 8% of all urinary tract neoplasms and of these greater than 90% are urothelial carcinomas. Haematuria and lumbal pain are the major symptoms. In a 72-year-old woman hospitalized for acute myocardial infarction, mediastinal lymphadenopathy is detected incidentally as well as a left supraclavicular lymph node, approximately 1.5 cm in diameter, from which samples were taken for cytological analysis. The smears revealed a number of single, very large cells, with distinct anisonucleosis and eccentric nuclei, often with large nucleoli and tiny granules in a prominent cytoplasm. Immunocytochemical staining showed positivity for CK18, 20 and 7 and negativity for vimentin, HMB45, AFP, thyreoglobulin, synaptophysin and chromogranin. The findings indicate malignant epithelial cells, most probably of the transitional cell epithelium. Urine sediment analysis of 3 samples discovered cells identical to those found in the lymph node sample. Further diagnostic tests (abdominal ultrasound, MR, PET-CT, cystoscopy) confirmed the presence of a tumour in the pyelon of the right kidney, which had caused an obstruction and atrophy of the right kidney. The patient started to receive chemotherapy, however metastases have been detected (by scintigraphy and PET-CT) in the skelet and a lymph nodes. This work confirms the clinically valuable role of cytology (exfoliative and FNA) in the diagnosis of rare occurrences and localizations of malignant tumours. In this case, cytology detected the presence of malignant cells in the lymph node and in the urine much before the onset of clinical signs of the disease before other diagnostic methods. draz_ezgeta@hotmail.com 119 4 th Croatian Congress of Clinical Cytology / 1 st Croatian Symposium of Analytical Cytology / 2 nd Croatian Symposium of Cytotechnology
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Final programme and abstract book
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UTORAK, 13.10.2009. SRIJEDA, 14.10.
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4. Hrvatski kongres kliniËke citologije 4th Croatian Congress ... - Penta

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