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4. Hrvatski kongres kliniËke citologije 4th Croatian Congress ... - Penta

4. Hrvatski kongres kliniËke citologije 4th Croatian Congress ... - Penta

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<strong>4.</strong> <strong>Hrvatski</strong> <strong>kongres</strong> <strong>kliniËke</strong> <strong>citologije</strong> / 1. <strong>Hrvatski</strong> simpozij analitiËke <strong>citologije</strong> / 2. <strong>Hrvatski</strong> simpozij citotehnologije<br />

78<br />

Klinička citologija - Usmena predavanja<br />

A CORRELATIVE STUDY OF HISTOLOGY AND IMPRINT CYTOLOGY OF GASTRIC<br />

MUCOSA BIOPSY IN THE DIAGNOSIS OF GASTRIC CANCER<br />

Fuštar-Preradović Lj1 , Coha B2 , Pajić-Penavić I3 1 Department of Pathology, Forensic Medicine and Cytology, General Hospital<br />

“Dr. Josip Benčević”, Slavonski Brod, Croatia<br />

2Department of Internal Medicine, General Hospital “Dr. Josip Benčević”,<br />

Slavonski Brod, Croatia<br />

3 Department of Otorhinolaryngology and Maxillofacial Surgery, General Hospital<br />

“Dr. Josip Benčević”, Slavonski Brod, Croatia<br />

The aim of the paper is to establish the value of gastric mucosa imprint cytology in detection<br />

of gastric cancer. 389 biopsy samples, taken from patients by endoscopic examination,<br />

with suspected diagnosis of stomach cancer were analyzed. Each specimen was<br />

first submitted to slide imprinting and then formalin fixed for further routine histopathology<br />

treatment. The imprints were air dried for cytological analysis, stained according to<br />

May- Grünwald-Giemsa and analyzed under a light microscope. 194 specimens were<br />

adequate for final comparison of gastric cancer detection methods. Using pathological<br />

and histological analyzes gastric cancer was found in 45 specimens and cytological<br />

analysis detected it in 63 specimens. Combining these two methods cancer was found in<br />

67 specimens. Patients having positive cytological finding and negative pathohistologic<br />

finding went for repeated gastroscopy with biopsy. All patients with positive findings were<br />

operated and the obtained material was entirely pathohistologically examined. Cancer<br />

was found in 67 patients. Cytological analysis of the imprints of bio-optic material of the<br />

stomach mucosa increases number of positive findings in preoperative stage of stomach<br />

cancer diagnosis. The biggest advantage of the method is its speed, simplicity and low<br />

price. All information on morphological changes of mucosa is also pathohistologically<br />

checked, because taking of imprints does not damage the specimen.<br />

ljubica.fustar.preradovic@sb.htnet.hr

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