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Figure 3-12 Gray matter density, group-difference statistical maps showing gray matter density increase (and whitematter density decrease) in the ALC subjects relative to controls (in nonscaled space). Shades of green to yellowrepresent positive Pearson’s correlation coefficients (increased gray matter density in ALC subjects) and shades ofpurple and pink represent negative Pearson’s correlation coefficients (decreased gray matter density in ALC subjects)according to the color bar on the right (range of Pearson correlation coefficients from –1 to +1). Regions shownin red correspond to correlation coefficients that show significant increase in gray matter in the ALC subjects relativeto controls at a threshold of p = 0.01. Regions shown in white correspond to correlation coefficients that showsignificant decrease in gray matter in the ALC subjects relative to controls at a threshold of P = 0.01. The Sylvianfissure (SF) and central sulcus (CS) are highlighted for anatomical reference. See color insert. (Sowell et al., 2002a.)Mapping Adolescent Brain Change 77