Nutrition and HIV/AIDS: A Training Manual - Linkages Project

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PurposeTo provide knowledge and skills for thenutritional management of drug andfood interactions in HIV/AIDS therapyNutrition and HIV/AIDS: A Training ManualSession 9Session OutlineRationale• Common types of drugs taken• Drug and food interactions• Nutritional implications• Appropriate dietary responses• Assessment questions and analysis• PLWHA are at high risk of malnutritionbecause of virus progression• PLWHA take several medications• Drugs can interact with each other andwith food and may reduce food intake oraffect nutrient absorption and metabolismGoal of Managementof Drug-Food InteractionsDrug and food interactions should beimmediately addressed to:• Prevent weight loss and malnutrition• Improve medication efficacy• Improve client adherence to treatmentTypes of Drugs Taken•Antiretrovirals(ARVs)• Antifungals• Antibiotics• Antimalarials• Anti-helminthics• Dietary supplements• Traditional therapies
Main Food and DrugInteractions1. Food effects on drug efficacy2. Medication effects on nutrient absorption,metabolism, distribution, and excretion3. Side effects of medication on food intake andnutrient absorption4. Medication and food interactions causingunhealthy side effectsFOOD INTAKEenhances orinhibitsDRUG EFFICACYFood reduces absorption of• Aspirin (analgesic)• Isoniazid (antituberculosis)• Rifampin (antituberculosis)• Indinavir (ARV)FOOD INTAKEenhancesor InhibitsDRUGSenhanceor inhibitDRUG EFFICACYA high-fat diet enhances the bioavailabilityof some ARVs, such as Tenovir, but reducesabsorption of others, such as Indinavir andZidovidune.NUTRIENT ABSORPTION AND METABOLISMIncreased nutrient intake is needed for• Isoniazid + vitamin B 6•Rifampin+ vitamin DDRUGSenhanceor inhibitNUTRIENT ABSORPTION AND METABOLISMMany protease inhibitors may causechanges in lipid levels and insulinresistance.• Reduce intake of saturated fats and sugar.SIDE EFFECTS OF DRUGSaffectFOOD INTAKE AND NUTRIENTABSORPTIONSide effects requiring dietary responses• Changes in taste, nausea, and anorexia• Bloating, heartburn, and constipation• Vomiting and diarrhea
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Regional Centrefor Quality ofHealth
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ACKNOWLEDGMENTSThis training manual
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ABBREVIATIONS AND ACRONYMSACCAIDSAN
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INTRODUCTIONThe coexistence of high
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ContentThe content is arranged in t
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The sessions can also be taught in
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OutlineContent Methodology TimingDe
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LECTURE NOTES 1: THE BASICS OF HIV/
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gradually weakened. The infected pe
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increase in HIV prevalence of 60 pe
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infection may have a rapid onset, l
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• Dot-blot immunobinding assayUri
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• Removal of children from school
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effectively, care and support inter
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DISCUSSION POINTS 1================
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Recommended preparation1. Be famili
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LECTURE NOTES 2: LINK BETWEEN NUTRI
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AIDS, the impairment of immune func
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for healthy, non-HIV-infected peopl
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Low blood levels of several nutrien
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• Finally, a study of AIDS patien
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EXERCISE 2=========================
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SESSION 3 NUTRITION ACTIONS FOR PEO
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Required materials• LCD or overhe
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McDermott, AY, A Shevitz, T Knox, R
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Goals of nutritional care and suppo
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• Circumferences of the waist, hi
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Consider the phase of the HIV infec
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Promote adequate nutrient intake (s
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Stages of illness and symptoms. Sym
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TherapyNitrogenretention[g/day]Rate
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Nutrient supplements for people liv
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Conclusion (slide 31)Nutritional ca
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HANDOUT 3.1 Case studies in HIV and
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HANDOUT 3.2 Safe Food Handling Prac
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OutlineContent Methodology Timing1.
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Recommended preparation• Be famil
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PVO-USAID Steering Committee on Mul
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Nutritional care and support of peo
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In this session “food security co
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HIV/AIDS attacks food security not
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• Human capital: Reduced producti
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Food-insecure populations may also
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Food security constraints to nutrit
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Pregnant and lactating women (slide
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Implementation of nutritional care
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demand these foods. A good assessme
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Counselors should be aware of and i
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Conclusion (slide 36)The capacity t
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UNAIDS and WHO. 2002. AIDS epidemic
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1. How does poor food availability
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5. Will referrals and targeting of
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SESSION 5 NUTRITIONAL MANAGEMENT OF
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Required materials• LCD or overhe
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LECTURE NOTES 5: NUTRITIONAL MANAGE
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Figure 2 Cycle of malnutrition and
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IV. Late symptomatic phase (full-bl
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The following symptoms may also neg
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• Enables greater food intake by
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EXERCISE 5=========================
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HANDOUT 5.1 Caring for symptoms ass
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Illness Diet Care and nutrition pra
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SESSION 6 NUTRITIONAL CARE AND SUPP
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Recommended preparation• Be famil
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———. 1998. Randomised trial o
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LECTURE NOTES 6: NUTRITIONAL CARE A
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The stigma associated with HIV can
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of malnutrition, which increases th
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adolescent mother, growth and devel
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HIV infection increases the energy
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Anemia is common during HIV infecti
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The use of high levels of supplemen
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Nutritional care and support for th
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Management of secondary infections
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A. Nutrition history• Dietary int
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• Income, housing, amenities for
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multiple nutrient supplement, where
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Management of diet-related HIV prob
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Infant feeding options and risks (s
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insecurity and may increase malnutr
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Seumo-Fosso, E, and B Cogill. 2003.
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HANDOUT 6.1 Health Sector and Mater
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HANDOUT 6.2 A Guide to Nutritional
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• Educational levelLactating moth
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Did the counselor ask about: YES NO
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HANDOUT 6.4 Practical Consideration
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HANDOUT 6.5 Checklist for Nutrition
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HANDOUT 6.7 Dietary Management of C
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Dietary problemFeverNutritional int
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1. How could HIV infection affect R
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• Nutritional status, dietary int
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• Rita’s dietary intake and eat
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• Eating smaller, more frequent e
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• How was the nutritional assessm
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Estimated time: 120 minutes excludi
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Suggested reading materialsCoutsoud
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LECTURE NOTES 7: INFANT FEEDING AND
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• A viral, bacterial, or parasiti
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DNA (cell-associated virus) in colo
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Mucosal integrity (slide 18)Studies
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PMTCT interventions are most effect
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Breastfeeding techniquesIt is espec
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women with HIV/AIDS for additional
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• Providing skin-to-skin contact
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suitable for replacement feeds befo
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• Administration of ZVD and Lamiv
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Coutsoudis, A, et al. 2001. Are HIV
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Semba, RD, N Kumwenda, D Hoover, et
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Case study 1A school teacher, Regin
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• How would you respond to Hilary
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HANDOUT 7.2 PMTCT Decision-Making A
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OutlineContent Methodology Time1. E
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Suggested reading materialsAgostoni
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LECTURE NOTES 8: NUTRITION AND HIV/
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Despite these statistics, it is dif
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Etiology of growth failure among HI
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oys. Micronutrient deficiencies wil
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• Changes in eating behaviors ass
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• Address issues relevant and of
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Enhanced ARV therapy (slide 29)Chil
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• Refer children with severe maln
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DISCUSSION POINTS 8Questions for cl
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Action/activityNorman admitted to n
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• Allocate time for each activity
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Food Medication Interactionswww.foo
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• Describes information collected
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• Antimalaria drugs such as quini
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Food effects on drug efficacy (slid
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Some antiretroviral drugs may affec
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MedicationPurposeRecommended Tobe t
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intake and poor nutrient absorption
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Anti-acid medications containing ma
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women’s nutritional status. It is
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Health provider capacityHealth prov
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• What foods should not be taken
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Gelato, M. 2003. Insulin and carboh
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eferred him to the counselor for th
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Medication Purpose Recommended Tobe
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Medication Purpose Recommended Tobe
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Side effects of each drug?Side effe
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PurposeTo provide basic information
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Factors in Transmissionand Vulnerab
Page 292 and 293: Impact on the Education Sector• D
Page 294 and 295: AcknowledgmentNutrition and HIV/AID
Page 296 and 297: Body Habitus ChangesMetabolic chang
Page 298 and 299: PurposeTo provide general nutrition
Page 300 and 301: Stages of HIV Disease andNutritionI
Page 302 and 303: IncreaseVitamin and Mineral IntakeS
Page 304 and 305: Lipodystrophy• Means fat maldistr
Page 306 and 307: PurposeTo introduce the constraints
Page 308 and 309: Effect of AIDS on Crop ProductionCr
Page 310 and 311: Pregnant and Lactating WomenFood an
Page 312 and 313: Session 5 Nutritional Management of
Page 314 and 315: Rationale, Cont.Importance of Manag
Page 316 and 317: Session 6 Nutritional Care and Supp
Page 318 and 319: Vulnerabilityof Women and Young Gir
Page 320 and 321: What Is Not KnownComparison of Nutr
Page 322 and 323: Purposeof Nutrition Care and Suppor
Page 324 and 325: Greatest Impact of NutritionImprove
Page 326 and 327: Size of the Problem in Africa• >3
Page 328 and 329: Possible Mechanisms ofTransmissionA
Page 330 and 331: Prevention-to-Care ContinuumInterve
Page 332 and 333: Session 8 Nutritional Care for Youn
Page 334 and 335: ChildrenBorn to HIV-Positive Mother
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Page 338 and 339: Enhanced ARV Therapy• To reduce v
Page 340 and 341: Care of the Terminally Ill ChildWhy
Page 344 and 345: SIDE EFFECTS OF DRUGSaffectFOOD INT
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