PABI Plan - The Sarah Jane Brain Project

Program Director/Principal Investigator (Last, First, Middle):
End Date: 07/31/2010
Project Goals: The goal of this research is to demonstrate the capacity to improve management of mTBI presenting to the Emergency
Department by the systematic application of the Acute Concussion Evaluation (ACE) and the ACE Care Plan. We will conduct a pilot
implementation study that will provide important evidence for improving identification, diagnosis and management of mTBI in the
ED setting. Specific Aim 1. Evaluate the feasibility of the ACE and ACE Care Plan for standardized implementation in the ED
setting. Specific Aim 2. Determine if the ACE-ED and ACE-ED Care Plan can be implemented by the ED staff and disseminated to
the Primary Care Providers (PCP). Specific Aim 3. Determine if routine use of the ACE-ED and ACE-ED Care Plan will improve
patient/family follow-up behavior and patient recovery.
Title: Outcome Measurement of mTBI in Children and Adolescents (7528)
Source: CDC CCU323352-03
Status: Completed
Role: Principal Investigator
% Effort: 35
Start Date: 09/30/2003
End Date: 12/31/2008
Project Goals: The major goal of this study is to develop and validate a test battery for children, 5-18 years, that is easily administered
by technical personnel, portable, and repeatable while sensitive in detecting and monitoring neurocognitive and behavioral outcomes
of mTBI. The test will be developed and normed on over 1,000 children across the 5-18 year age range, examining performance in
boys and girls and at-risk children with learning and attentional problems. 160 children and adolescents (80 boys, 80 girls) who have
sustained mTBI will be recruited from the CNMC Emergency Dept. and the UPMC/ CNMC Sports Concussion programs and
followed serially during the first two weeks post-injury and up to one year to detect deficits and monitor recovery outcome in
cognitive performance and real-world home and school functioning.
Title: Neurobehavioral and Psychosocial Evaluation Core (General Clinical Research Center) (Mark Batshaw, M.D.,
Principal Investigator) (0198)
Source: NIH 5 P30 HD40677-08 (Gallo, PI)
Status: Active
Role: Director, Core Laboratory
% Effort: 10
Start Date: 07/01/02
End Date: 11/30/2009
Project Goals: 1) provide access to an extensive battery of neuropsychological testing services; 2) develop and administer
neurobehavioral tasks for relevant protocols; 3) provide consultation to GCRC investigators on the proper design and use of
neurobehavioral and neuropsychological measures in research studies; and 4) train investigators and their staff in the use of these
measures.
Title: Neurobehavioral Evaluation Core (Intellectual and Developmental Disabilities Research Center) (V. Gallo, PhD,
Principal Investigator) (0198)
Source: NIH
Status: Active
Role: Director, Core Laboratory
% Effort: 5
Start Date: 07/01/2006
End Date: 06/30/2011
Project Goals: 1) provide access to an extensive battery of neuropsychological testing services; 2) develop and administer
neurobehavioral tasks for neuroimaging protocols, including fMRI projects through the Neuroimaging Core; 3) provide consultation to
IDDRC investigators on the proper design and use of neurobehavioral and neuropsychological measures in research studies; and 4)
train investigators and their staff in the use of these measures.
Title: Neurofibromatosis Consortium (R. Packer, M.D., Principal Investigator)
Source: DoD
Status: Active
Role: Chair, Neurocognitive Committee
% Effort: 10
St. Date 07/01/2006
End Date 12/31/2011
Project Goals: Provide leadership and guidance to the Neurocognitive committee in developing research protocols that investigate the
neuropsychological outcomes in NF clinical trials.
PHS 398/2590 (Rev. 11/07) Page 3 Continuation Format Page