PABI Plan - The Sarah Jane Brain Project

7. Determine how we can use technology to best promote child/young adult and family
function
Research – New Therapies
1. Characterize and validate new experimental models for different types of developmental
brain injuries
2. Develop mechanism-based age-appropriate therapies and demonstrate effectiveness in
translational models. In this setting, therapies should be thought of in a broad sense and
not be limited to simply medications or physical rehabilitation, but also nutritional,
educational, neural activation strategies, bio-behavioral, family-based and certainly,
combination therapies
3. Rapidly disseminate experimental results to practicing clinician networks and engage in
interdisciplinary design of appropriate clinical trials
4. Demonstrate efficacy of novel and innovative therapeutic interventions in real-life
situations prior to establishing guidelines/protocols. However, research does not end at
this point – ongoing investigations must be conducted to monitor implementation,
demonstrate ability to be generalized or specific indications for therapy, and follow longterm
functional outcomes.
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