PABI Plan - The Sarah Jane Brain Project

4. Improve the specific identification of “mild” TBI in the very young child (e.g., panel of
clinical biomarkers, utility of baseline cognitive testing/ symptom assessment, etc.)
5. Develop an effective professional training/ educational program for
identification/classification of children with “mild” TBI.
6. Investigate underlying neuropathophysiologic indicators for “mild” TBI, including definition
of genetic risk factors, use of neuroimaging, and specifying other physiologic biomarkers for
outcomes from pediatric “mild” TBI.
7. Develop age-specific neuroprotective strategies for children after “mild” TBI.
8. Develop age-appropriate experimental laboratory models relevant to children after “mild”
TBI.
9. Investigate effective referral mechanisms across the full continuum of care and services.
10. Develop effective educational program within the schools for the proper identification,
classification, and treatment of children with “mild” TBI with a focus on the management of
cognitive exertion during recovery.
11. Develop prospective longitudinal controlled psychiatric studies of children with “mild” TBI.
12. Implement data-guided psychiatric surveillance and management of children with “mild”
TBI.
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