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108 PART 2 Antibacterial Drugs<br />

syphilis, pelvic inflammatory disease (with cefoxitin).<br />

Use as an alternative to ciprofloxacin in bioterrorism<br />

scenarios (they are active against anthrax,<br />

plague, tularemia). Use for malaria prophylaxis<br />

and treatment. Tigecycline may have a role in the<br />

treatment of complicated polymicrobial infections,<br />

such as intra-abdominal infections and complicated<br />

skin and skin structure infections.<br />

Don’t Forget!<br />

Ask patients if they take mineral supplements<br />

(like calcium and iron) at home. Just because supplements<br />

are not on a patient’s medication profile<br />

does not mean they do not take them. A patient<br />

who washes down a tetracycline with a calcium<br />

supplement or even a glass of milk may completely<br />

negate an otherwise brilliant therapeutic plan.

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