antibioticsbooks

264 PART 6 Antiparasitic Drugs
world except Southeast Asia) and prophylaxis
against malaria in travelers to those regions
Quinine/quinidine: Treatment of uncomplicated
malaria (quinine) or severe malaria (quinidine)
in combination with doxycycline, tetracycline,
or clindamycin; not used for prophylaxis
Primaquine: Treatment of uncomplicated malaria
because of P. vivax or P. ovale in combination
with a second agent, prophylaxis against
malaria in travelers where P. vivax is the principal
species, in combination with clindamycin,
and in treatment of mild-to-moderate
Pneumocystis pneumonia
Don’t Forget!
As with bacterial infections, the progression of antimicrobial
resistance makes treatment of and prophylaxis
against malaria difficult. Because most
clinicians deal with malaria infrequently, there is
no shame in double-checking national guidelines to
make sure you are using the most appropriate regimen
for your patient. The CDC even has a malaria
hotline to help clinicians deal with treatment of
cases [(770) 488-7788].