antibioticsbooks

More documents

Recommendations

Info

286 appendix 2 Table A–2 Clinically Useful Spectra of Activity for Empiric Antibiotic Selection MSSA MRSA Strep Enterococci GNR Pseudo Anaerobes* Atypicals Doxycycline 1 1/2 1 1/2 1 11 Tigecycline 11 11 11 11 11 11 11 Clindamycin 11 1/2 11 1 Vancomycin 11 11 11 11 Azithromycin 1/2 1 1 11 Metronidazole 11 Telithromycin 1 11 1 11 Daptomycin 11 11 11 11 Linezolid 11 11 11 11 Quin/Dalf 11 11 11 11 Nitrofurantoin 1 1 Fosfomycin 1 11 TMP/SMX 11 1 1/2 1 Key: 11 5 good activity; 1 5 some activity; 1/2 5 variable activity * Anerobes here include GI anerobes except Clostridium difficile, for which the only antibiotics with good clinical activity on this list are vancomycin and metronidazole. † Aminoglycosides have useful synergistic activity versus Gram-positive cocci only when paired with a cell-wall active agent (e.g., beta-lactams, vancomycin). Abbreviations: MSSA 5 methicillin-sensitive Staphylococcus aureus; MRSA 5 methicillin-resistant Staphylococcus aureus; Strep 5 streptococci; GNR 5 aerobic Gram-negative rods (in general, and not including P. aeruginosa); Pseudo 5 Pseudomonas aeruginosa; Imi/mero/dori5imipenem, meropenem, doripenem; Gent/tobra5gentamicin, tobramycin; Amp/sulb 5 ampicillin/sulbactam; Pip/tazo 5 piperacillin/tazobactam; Quin/dalf 5 quinupristin/dalfopristin; TMP/SMX 5 trimethoprim/sulfamethoxazole.
appendix 2 Spectrum of Activity 287 Table A–3 Clinically Useful Spectra of Activity for Empiric Antifungal Selection Candida albicans, C. parapsilosis, C. tropicalis Candida glabrata Candida krusei Cryptococcus Aspergillus Zygomycetes Fluconazole 11 1/2 11 Itraconazole 11 1/2 1/2 11 1 Voriconazole 11 1 11 11 11 Posaconazole 11 1 11 11 11 1 Amphotericin 11 1 11 11 11 11 Anidula/caspo/mica 11 11 11 1 Key: 11 5 good activity; 1 5 some activity; 1/2 5 variable activity Abbreviation: Anidula/caspo/mica 5 anidulafungin, caspofungin, micafungin.
Page 1 and 2:
Antibiotics Simplified third EDITIO
Page 3 and 4:
Contents Acknowledgments Introducti
Page 5 and 6:
Contents v Chapter 28: Antifungal A
Page 7:
Acknowledgments Our thanks go to th
Page 10 and 11:
x Introduction ■■ How to Use Th
Page 13:
New to the Third Edition The Third
Page 17 and 18:
The Wonderful World of Microbiology
Page 19 and 20:
chapter 1 Microbiology 5 More like
Page 21 and 22:
chapter 1 Microbiology 7 Influenza
Page 23 and 24:
chapter 1 Microbiology 9 Bacilli An
Page 25 and 26:
chapter 1 Microbiology 11 Gram-nega
Page 27 and 28:
chapter 1 Microbiology 13 Cocci Aer
Page 29 and 30:
General Approach to Infectious Dise
Page 31 and 32:
chapter 2 Infectious Diseases 17 Th
Page 33 and 34:
chapter 2 Infectious Diseases 19 Su
Page 35 and 36:
chapter 2 Infectious Diseases 21 al
Page 37 and 38:
Antibiotic Pharmacokinetics 3 The t
Page 39 and 40:
chapter 3 Pharmacokinetics 25 Table
Page 41 and 42:
chapter 3 Pharmacokinetics 27 can b
Page 43 and 44:
chapter 3 Pharmacokinetics 29 becau
Page 45:
chapter 3 Pharmacokinetics 31 Table
Page 48 and 49:
34 PART 1 Antibiotic Therapy No vis
Page 50 and 51:
36 PART 1 Antibiotic Therapy Table
Page 52 and 53:
38 PART 1 Antibiotic Therapy done i
Page 55 and 56:
Adverse Consequences of Antibiotic
Page 57 and 58:
chapter 5 Adverse Consequences 43 f
Page 59 and 60:
chapter 5 Adverse Consequences 45 U
Page 61:
Antibacterial Drugs Part 2
Page 64 and 65:
50 PART 2 Antibacterial Drugs to be
Page 66 and 67:
52 PART 2 Antibacterial Drugs is ne
Page 68 and 69:
54 PART 2 Antibacterial Drugs Spect
Page 71 and 72:
Antistaphylococcal Penicillins Agen
Page 73 and 74:
Aminopenicillins Agents: amoxicilli
Page 75:
chapter 6 Beta-Lactams 61 Don’t F
Page 78 and 79:
64 PART 2 Antibacterial Drugs Adver
Page 80 and 81:
66 PART 2 Antibacterial Drugs enhan
Page 82 and 83:
68 PART 2 Antibacterial Drugs good
Page 84 and 85:
70 PART 2 Antibacterial Drugs Cefaz
Page 86 and 87:
72 PART 2 Antibacterial Drugs ■
Page 88 and 89:
Page 91 and 92:
Third-Generation Cephalosporins Age
Page 93:
chapter 6 Beta-Lactams 79 biliary e
Page 96 and 97:
82 PART 2 Antibacterial Drugs but o
Page 98 and 99:
84 PART 2 Antibacterial Drugs bind
Page 100 and 101:
Carbapenems Agents: imipenem/cilast
Page 102:
chapter 6 Beta-Lactams 89 and thus
Page 105 and 106:
Page 107 and 108:
94 PART 2 Antibacterial Drugs Mecha
Page 109 and 110:
96 PART 2 Antibacterial Drugs as be
Page 111 and 112:
98 PART 2 Antibacterial Drugs Spect
Page 113 and 114:
chapter 9 Aminoglycosides 103 equal
Page 115 and 116:
Aminoglycosides 9 Agents: gentamici
Page 117 and 118:
chapter 9 Aminoglycosides 103 equal
Page 119 and 120:
Tetracyclines and Glycylcyclines 10
Page 121 and 122:
chapter 10 Tetracyclines 107 admini
Page 123 and 124:
Macrolides and Ketolides 11 Agents:
Page 125 and 126:
chapter 11 Macrolides and Ketolides
Page 127 and 128:
Oxazolidinones 12 Agent: linezolid
Page 129:
chapter 12 Oxazolidinones 115 What
Page 132 and 133:
118 PART 2 Antibacterial Drugs Spec
Page 135 and 136:
Nitrofurans and Fosfomycin 14 Agent
Page 137:
chapter 14 Nitrofurans and Fosfomyc
Page 140 and 141:
Page 143 and 144:
Cyclic Lipopeptides 16 Agent: dapto
Page 145:
chapter 16 Cyclic Lipopeptides 131
Page 148 and 149:
Page 150 and 151:
136 PART 2 Antibacterial Drugs What
Page 152 and 153:
Page 154 and 155:
140 PART 2 Antibacterial Drugs Don
Page 156 and 157:
Page 158 and 159:
144 PART 2 Antibacterial Drugs Beca
Page 160 and 161:
146 PART 2 Antibacterial Drugs asso
Page 163 and 164:
Antimycobacterial Drugs 21 ■■ I
Page 165:
chapter 21 Antimycobacterial Drugs
Page 168 and 169:
154 PART 3 Antimycobacterial Drugs
Page 170 and 171:
Page 172 and 173:
Page 175 and 176:
Pyrazinamide 24 Agent: pyrazinamide
Page 177 and 178:
Ethambutol 25 Agent: ethambutol (EM
Page 179:
Antifungal Drugs Part 4
Page 182 and 183:
168 PART 4 Antifungal Drugs When th
Page 185 and 186:
Polyenes 27 Agents: amphotericin B,
Page 187 and 188:
chapter 27 Polyenes 173 1.5 mg/kg/d
Page 189 and 190:
Antifungal Antimetabolites 28 Agent
Page 191:
chapter 28 Antifungal Antimetabolit
Page 195 and 196:
Fluconazole The introduction of flu
Page 197:
chapter 29 Azoles 183 • The high
Page 200 and 201:
186 PART 4 Antifungal Drugs Adverse
Page 203 and 204:
Voriconazole The introduction of vo
Page 205 and 206:
chapter 29 Azoles 191 ■■ Import
Page 207 and 208:
Posaconazole Posaconazole is the ne
Page 209:
chapter 29 Azoles 195 inhibitors lo
Page 212 and 213:
198 PART 4 Antifungal Drugs Spectru
Page 215:
Antiviral Drugs Part 5
Page 218 and 219:
204 PART 5 Antiviral Drugs The unde
Page 221 and 222:
Anti-Herpes Simplex Virus and Varic
Page 223:
chapter 32 Anti-HSV and VZV Agents
Page 226 and 227:
212 PART 5 Antiviral Drugs Spectrum
Page 229 and 230:
Neuraminidase Inhibitors 34 Agents:
Page 231:
chapter 34 Neuraminidase Inhibitors
Page 234 and 235:
220 PART 5 Antiviral Drugs the comm
Page 236 and 237:
222 PART 5 Antiviral Drugs Spectrum
Page 238 and 239:
224 PART 5 Antiviral Drugs What The
Page 240 and 241:
226 PART 5 Antiviral Drugs Adverse
Page 242 and 243:
228 PART 5 Antiviral Drugs • NNRT
Page 244 and 245:
230 PART 5 Antiviral Drugs The drug
Page 246 and 247:
232 PART 5 Antiviral Drugs • The
Page 249 and 250: Integrase Inhibitors Agents: ralteg
Page 251: chapter 35 Antiretroviral Drugs 237
Page 254 and 255: 240 PART 5 Antiviral Drugs from hea
Page 256 and 257: 242 PART 5 Antiviral Drugs Spectrum
Page 258 and 259: 244 PART 5 Antiviral Drugs option f
Page 260 and 261: 246 PART 5 Antiviral Drugs Think of
Page 262 and 263: 248 PART 5 Antiviral Drugs ribaviri
Page 264 and 265: 250 PART 5 Antiviral Drugs administ
Page 267 and 268: Hepatitis B Nucleoside Analogs 39 A
Page 269: Antiparasitic Drugs Part 6
Page 272 and 273: 258 PART 6 Antiparasitic Drugs Tabl
Page 275 and 276: Quinolines 41 Agents: chloroquine,
Page 277 and 278: chapter 41 Quinolines 263 majority
Page 279 and 280: Atovaquone 42 Agents: atovaquone, a
Page 281: chapter 42 Atovaquone 267 Don’t F
Page 284 and 285: 270 PART 6 Antiparasitic Drugs Adve
Page 287 and 288: Pentamidine 44 Agent: pentamidine P
Page 289: chapter 44 Pentamidine 275 as appro
Page 292 and 293: 278 PART 6 Antiparasitic Drugs Spec
Page 294 and 295: Appendix 1 Selected Normal Human Fl
Page 296 and 297: Appendix 2 Spectrum of Activity A N
Page 298 and 299: 284 appendix 2 and thus less likely
Page 302 and 303: Appendix 3 Empiric Regimens for Com
Page 304 and 305: 290 appendix 3 Infection Common Pat
Page 306 and 307: 292 appendix 3 Infection Common Pat
Page 308 and 309: 294 Index Amoxicillin/clavulanate,
Page 310 and 311: 296 Index Broad-spectrum antibacter
Page 312 and 313: 298 Index Combivir, 221 Community-a
Page 314 and 315: 300 Index Eukaryotes, 5, 203 Extend
Page 316 and 317: 302 Index HIV (continued) anti-herp
Page 318 and 319: 304 Index Minimum bactericidal conc
Page 320 and 321: 306 Index PEG. See Polyethylene gly
Page 322 and 323: 308 Index Pseudomonas (continued) P
Page 324 and 325: 310 Index Sustained virologic respo
show all

antibioticsbooks

You also want an ePaper? Increase the reach of your titles

Delete template?

Save as template?