antibioticsbooks

chapter 6 Beta-Lactams 75
What They’re Good For
Upper respiratory tract infections, communityacquired
pneumonia, gonorrhea, surgical prophylaxis
(cefotetan, cefoxitin, cefuroxime).
Don’t Forget!
The cephamycins have good intrinsic anaerobic
activity, but resistance to them is increasing in
Bacteroides fragilis group infections. When using
them for surgical prophylaxis, limit the duration
of antibiotic exposure after surgery. If an infection
does develop, use alternative agents such as
beta-lactamase inhibitor combinations or another
Gram-negative agent with metronidazole.