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chapter 16 Cyclic Lipopeptides 131<br />

What It’s Good For<br />

Skin and skin structure infections caused by resistant<br />

Gram-positive organisms and staphylococcal<br />

bacteremia, including right-sided endocarditis.<br />

Daptomycin also has utility in enterococcal bacteremia,<br />

though it is not indicated or as well-studied<br />

for this use.<br />

Don’t Forget!<br />

Monitor CK concentrations and renal function for<br />

patients taking daptomycin, particularly if they<br />

are on other drugs toxic to skeletal muscle, like<br />

HMG-CoA reductase inhibitors.

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