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Index 297<br />

anaerobes and, 71, 73–75, 77,<br />

81, 84<br />

anaphylaxis and, 70<br />

antibacterial activity of, 38<br />

Bacteroides and, 75<br />

beta-lactamases and, 70, 73<br />

bleeding and, 74<br />

central nervous system<br />

infections and, 72, 74, 78<br />

Clostridium and, 78<br />

endocarditis and, 72<br />

Enterococci and, 71, 73, 77,<br />

81, 84<br />

fifth-generation, 83–85<br />

first-generation, 71–72<br />

fourth-generation, 81–82<br />

GNRs and, 71, 73, 75, 77, 78,<br />

81–84<br />

gonorrhea and, 75, 78, 79<br />

Gram-positive organisms and,<br />

73, 78, 81, 82<br />

Haemophilus and, 73<br />

hives and, 70<br />

introduction to, 69–70<br />

Lyme disease and, 79<br />

meningitis and, 78, 79, 82<br />

MRSA and, 50, 71, 73, 77, 81, 84<br />

MSSA and, 71, 72, 77, 81, 84<br />

Neisseria and, 73<br />

neutropenia and, 79, 82<br />

N-methylthiotetrazole<br />

(MTT), 74<br />

penicillin allergy and, 69–70<br />

phlebitis and, 58, 72<br />

pneumonia and, 75, 82, 84<br />

Pseudomonas and, 71, 73, 77,<br />

78, 81, 84, 85<br />

pyelonephritis and, 79<br />

renal function/dysfunction and,<br />

78–79<br />

respiratory tract infections<br />

and, 75, 79, 82<br />

second-generation, 73–75<br />

skin infections and, 72, 79, 84<br />

Staphylococci and, 50, 71–73,<br />

77, 81, 84<br />

Streptococci and, 71, 73, 77,<br />

78, 81, 84<br />

third-generation, 77–79<br />

urinary tract infections and,<br />

79, 82<br />

vitamin K and, 74, 78<br />

Cephalothin, described, 71–72<br />

Cephamycins, 74, 75<br />

Cerebrospinal fluid (CSF), 4<br />

concentrations of antibiotics<br />

in, 27, 29<br />

Gram-positive bacilli in, 9<br />

Cestodes, 257<br />

Chills, 172<br />

Chlamydia, 4, 98, 111<br />

C. trachomatis, 138<br />

Chlamydophila pneumoniae, 50<br />

Chloroquine, 258, 266<br />

described, 261–264<br />

Cidofovir, described, 211–213<br />

Cilastatin<br />

described, 87–89<br />

imipenem, 20–21<br />

Cinchonism, syndrome of, 263<br />

Ciprofloxacin, 20, 25, 108<br />

described, 97–100<br />

Cisplatin, 102<br />

Citrobacter, 12, 122<br />

CK. See Creatine kinase<br />

Clarithromycin, described,<br />

109–112<br />

Clavulanate. See Amoxicillin/<br />

clavulanate, described;<br />

Ticarcillin/clavulanate,<br />

described<br />

Clindamycin, 21, 258, 264<br />

described, 137–140<br />

Clostridium, 9, 118<br />

C. difficile, 22, 43, 78, 94, 95,<br />

117, 119, 138, 140, 145–146<br />

Cloxacillin, described, 57–58<br />

CMV. See Cytomegalovirus<br />

(CMV)<br />

CNS. See Central nervous system<br />

(CNS)<br />

Cobicistat, 235–237<br />

Coccidioides, 5, 167<br />

C. immitis, 168, 181<br />

Coccidioidomycosis, 183<br />

Colistin (colistimethate sodium),<br />

described, 141–144<br />

Colitis, 117

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