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Index 309<br />

Seizures, 118, 154, 158, 208<br />

beta-lactams and, 49–50, 88<br />

carbapenems and, 88–89<br />

Selective serotonin reuptake<br />

inhibitors (SSRIs), 114, 115<br />

Sensory system, minocycline<br />

and, 106<br />

Sepsis, 104, 143<br />

Serine protease enzymes, 245<br />

Serine protease inhibitors,<br />

described, 245–248<br />

Serratia, 12, 14, 122, 142<br />

Serum sickness, 41<br />

Shigella, 12, 134<br />

Single-dose therapy, of intestinal<br />

nematode infections, 270<br />

Sinusitis, 107<br />

Sirolimus, 199<br />

Skin/soft tissue infections, 20, 58,<br />

100, 107<br />

cephalosporins and, 72, 79, 84<br />

lincosamides and, 137, 139<br />

and skin structure infection,<br />

96, 115, 131<br />

S. maltophilia, 12, 14, 134, 142<br />

SMX. See Sulfamethoxazole<br />

(SMX)<br />

Sodium stibogluconate, 259<br />

Spectinomycin, described, 101–104<br />

Spirochetes, 106<br />

Staphylococcal bacteremia, 131<br />

Staphylococcal endocarditis, 130<br />

Staphylococcus, 98, 106, 110, 117,<br />

122, 125, 138, 154. See also<br />

MRSA (methicillin-resistant<br />

Staphylococcus aureus);<br />

MSSA (methicillin-sensitive<br />

Staphylococcus aureus)<br />

aminoglycosides and, 102<br />

beta-lactams and, 50, 58<br />

cephalosporins and, 50, 72, 73,<br />

77, 78, 81, 84<br />

glycopeptides and, 93–96<br />

penicillin and, 21, 51, 53, 57,<br />

59, 63, 65, 66, 72, 88<br />

S. aureus, 4, 5, 8, 21–22, 53,<br />

58, 134, 136, 138, 149<br />

S. epidermidis, 8, 10, 44<br />

S. saprophyticus, 8, 122<br />

Statins, 232<br />

Stavudine (d4T), described,<br />

221–224<br />

Sterile site, infection in, 4<br />

Stevens-Johnson syndrome, 134,<br />

138, 226<br />

Streptococcal pharyngitis, 60<br />

Streptococcus, 6, 10, 102, 117,<br />

126, 129<br />

antibiotic susceptibility break<br />

points, 36<br />

cephalosporins and, 71, 73, 77,<br />

81, 84<br />

penicillins and, 54–55, 59, 60,<br />

63, 64, 66, 87<br />

S. agalactiae, 9<br />

S. pneumoniae, 4, 5, 9, 10, 36,<br />

54–55, 78, 106, 109, 110,<br />

111, 113, 134<br />

S. pyogenes, 9, 110, 134,<br />

137, 138<br />

Streptogramins, described,<br />

125–127<br />

Streptomycin, described,<br />

101–104<br />

Stribild, 235–237<br />

Stroke, 230<br />

Strongyloides, 258, 270, 279<br />

S. stercoralis, 269, 278<br />

strongyloidiasis, 277, 278<br />

Substrates of drug metabolizing<br />

enzymes, 30<br />

Suicide, 226, 262<br />

Sulbactam. See also Ampicillin/<br />

sulbactam<br />

described, 65–68<br />

Sulfadiazine, 136<br />

described, 133–136<br />

pyrimethamine, 258<br />

Sulfadoxine, described, 133–136<br />

Sulfamethoxazole (SMX), 19, 21,<br />

123. See also Trimethoprim/<br />

sulfamethoxazole (TMP/<br />

SMX)<br />

described, 133–136<br />

Superinfection, antibiotic,<br />

42–43<br />

Susceptibility testing of<br />

antibiotics, 33–36

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