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Antiviral Drugs<br />

31<br />

■■<br />

Introduction to Antiviral Drugs<br />

The term virus has interesting meanings in popular<br />

culture: it is commonly used to describe something<br />

that has or can spread quickly from person<br />

to person, such as a computer virus or a “viral”<br />

video, a video that gains quick popularity through<br />

Internet or e-mail sharing. This usage represents<br />

a basic understanding of the high transmissibility<br />

of many respiratory viruses, such as influenza<br />

and the rhinoviruses that cause the common cold.<br />

However, many less-understood viruses, particularly<br />

those that cause chronic disease, can be<br />

confusing.<br />

The world of viruses is very different from that<br />

of prokaryotes and eukaryotes. Viruses are dependent<br />

on cells to replicate and cannot perpetuate<br />

without them. They are considerably smaller than<br />

eukaryotes and even much smaller than most<br />

prokaryotes, though they vary widely in size (see<br />

Figure 1–2). They are relatively simple organisms<br />

compared with prokaryotes or eukaryotes, but they<br />

outnumber all life forms on earth. Scientists have<br />

debated for many years about whether viruses are<br />

life forms or not, and no clear consensus yet exists.

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