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chapter 2 Infectious Diseases 19<br />

Suspect infection<br />

Culture suspected sites<br />

Begin empiric therapy for<br />

likely pathogens<br />

Gram stain<br />

Identification<br />

Susceptibilities<br />

Change to definitive therapy for patient-specific pathogens<br />

Figure 2–2<br />

General Approach to Infectious Diseases<br />

is important that clinicians continuously consider<br />

the need to transition to definitive therapy. Overly<br />

broad-spectrum therapy has consequences, and the<br />

next infection is likely to be harder to treat. Keep<br />

in mind the general pathway for the treatment of<br />

infectious diseases shown in Figure 2–2.<br />

Examples of Therapy<br />

Here are a few examples of each type of therapy:<br />

Prophylaxis Therapy<br />

• Trimethoprim/sulfamethoxazole (TMP/SMX)<br />

to prevent Pneumocystis jirovecii (formerly<br />

carinii) pneumonia in a patient on cyclosporine<br />

and prednisone after a liver transplant

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