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306 Index<br />

PEG. See Polyethylene glycol<br />

(PEG)<br />

Pegylated interferon-a 2a,<br />

described, 241–244<br />

Pegylated interferon-b 2b,<br />

described, 241–244<br />

Pelvic inflammatory disease, 108<br />

Penciclovir, 208<br />

Penicillin(s), 29, 45, 49, 117. See<br />

also individual drugs<br />

aerobes and, 67<br />

allergy and carbapenems, 89<br />

allergy and cephalosporins,<br />

69–70<br />

allergy and monobactams, 92<br />

amino, 52, 59–61<br />

anaerobes and, 57, 59, 63, 65,<br />

66, 67<br />

antibacterial activity of, 38<br />

antipseudomonal, 52, 63–64<br />

antistaphylococcal, 52, 57–58, 72<br />

beta-lactamases and, 57–59,<br />

63, 65–68, 70<br />

diabetic ulcers and, 68<br />

diarrhea and, 51–52, 60, 67<br />

E. coli and, 60, 64, 66<br />

endocarditis and, 55, 58, 61<br />

Enterococci and, 54, 57–61, 63,<br />

64, 66<br />

GNRs and, 51, 52, 57–60, 63,<br />

65–67<br />

Gram-positive organisms and,<br />

59, 64<br />

Haemophilus and, 59, 63<br />

introduction to, 51–52<br />

IV, 52, 53<br />

MRSA and, 57, 66, 83, 84, 88<br />

MSSA and, 57, 58, 66<br />

natural, 51, 52, 53–55<br />

otitis media and, 60<br />

penicillin G, 53–55, 65<br />

penicillin V, 53–55<br />

pharyngitis and, 55, 60<br />

phlebitis and, 58, 72<br />

pneumonia and, 68<br />

Pseudomonas and, 59,<br />

63–64, 66<br />

renal function/dysfunction and,<br />

51, 58<br />

respiratory tract infections<br />

and, 60<br />

skin infections and, 58<br />

Staphylococci and, 21, 51, 53,<br />

57, 59, 63, 65, 66, 72, 88<br />

Streptococci and, 54–55, 59, 60,<br />

63, 64, 66, 87<br />

syphilis and, 55<br />

Treponema and, 54<br />

UTIs and, 64<br />

Penicillin G, described, 53–55<br />

Penicillin V, 53–55<br />

Penile ulcers, 212<br />

Pentamidine, 258, 266<br />

described, 273–275<br />

Peptic ulcer disease, 111<br />

Peptidoglycan, 6, 7, 11, 94, 121<br />

cell wall polysaccharides<br />

components, 149<br />

Peptococcus, 8<br />

Peptostreptococcus, 8, 118<br />

Peripheral neuropathy, 114, 118<br />

Peripheral vascular disease, 28<br />

Permethrin, 277, 279<br />

Pharmacokinetic enhancers, 236<br />

Pharmacokinetic/<br />

pharmacodynamic (PK/PD)<br />

parameters, 38–39<br />

Pharmacokinetics, 141<br />

Pharmacotherapy<br />

antifungal, 168–169<br />

for HBV and HCV infection,<br />

243<br />

of infectious diseases, 15<br />

of mycobacterial disease, 150<br />

tuberculosis, 157<br />

of viral infections, 205<br />

Pharyngitis, 55<br />

streptococcal, 60<br />

Phenytoin, 270<br />

Phlebitis, 58, 72, 126<br />

Phosphorylation, 207, 211<br />

Photosensitivity, 98, 106<br />

Pinworms, 269<br />

Piperacillin, described, 63–68<br />

Piperacillin/tazobactam, 20,<br />

21, 22<br />

described, 65–68<br />

Plague, 100, 101, 108

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