Elephants Elephants - Wildpro - Twycross Zoo
Elephants Elephants - Wildpro - Twycross Zoo
Elephants Elephants - Wildpro - Twycross Zoo
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than 20mls should be injected at any one site to avoid swelling and<br />
inflammation. Abscesses form readily in elephants and it is essential that the<br />
skin is cleaned thoroughly with disinfectant before an injection is made.<br />
Injections in hind legs require 6-9cm needles. Intravenous injections are<br />
generally made into the veins on the posterior aspect of the ear, but leg veins<br />
can be used in some animals. Perivascular injection should be avoided as it<br />
may lead to local necrosis & sloughing particularly when using flunixin<br />
meglumine (Finadyne). For large volumes of intravenously administered<br />
drugs, an intravenous cannula is advised.<br />
<strong>Elephants</strong> should be restrained when being injected and the veterinarian<br />
MUST always bear in mind safety considerations should the animal object.<br />
It is highly questionable whether adequate absorption occurs from the<br />
subcutaneous space in elephants and generally this route should be avoided.<br />
However, it is possible that some drugs could be administered per rectum.<br />
One report describes the pharmacokinetics of rectally administered<br />
metronidazole (Gulland and Carwardine 1987).<br />
In very general terms, antibiotics and other drugs are given at same dose rates<br />
as for horses and cattle (Schmidt 1986) unless specific pharmacokinetic data is<br />
available for the elephant. Such data is unavailable for the majority of drugs.<br />
A table of known effective dose rates for some antibiotics is given below.<br />
Olsen (1999) gives details of weight estimation and dosage calculations.<br />
Drug Dose Route Frequency Comments<br />
Amoxycillin 11mg/kg IM 1 x daily (Olsen 1999)<br />
Ampicillin 8mg/kg PO 2-3 x daily (Olsen 1999)<br />
Enrofloxacin 2.5mg/kg PO 1 x daily (Olsen 1999)<br />
Enrofloxacin 1.25mg/kg PO 2 x daily (Olsen 1999)<br />
Gentamycin 4.4mg/kg IM/ IV 1 x daily (Olsen 1999)<br />
Isoniazid 5mg/kg PO 1 x daily (Mikota et al 2001)<br />
Metronidazole 15mg/kg PR 1 x daily Give iron supplement<br />
Pyrazinamide 25-35<br />
mg/kg<br />
PO 1 x daily (Mikota et al 2001)1<br />
Rifampicin 7.5-10<br />
mg/kg<br />
PO 1 x daily (Mikota et al 2001)<br />
Tetracycline 20mg/kg IM Every<br />
48hrs<br />
(Olsen 1999)<br />
Trimethaprimsulphamethoxazole<br />
22mg/kg PO 2 x daily (Olsen 1999)<br />
Tylosin 12mg/kg IM 1 x daily (Schmidt 1986)<br />
Anaesthesia and Sedation<br />
This section provides general information on the topic. It is not intended to be<br />
a comprehensive guide and for more detailed information reference should be<br />
made to the veterinary texts listed in the reference list e.g. (Fowler et al 2000)<br />
(Fowler and Miller 1998).<br />
Sedatives include: