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Elephants Elephants - Wildpro - Twycross Zoo

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Table 2. Doses for individual supplements based on relative vitamin E potency, using rate for<br />

Perissodactyls (1 IU / kg body weight / day). Divide by half for Artiodactyl species at any<br />

equivalent body weight. Relative costing is intended for guidance only.<br />

Equivite Original 10<br />

£0.03<br />

Equivite VitE & Se 3<br />

£0.04<br />

<strong>Zoo</strong>-E-Sel 5<br />

£0.04<br />

body weight (kg)<br />

100 250 500 1000 1750 4000 6000<br />

Supplement dose (g) and approximate cost*<br />

25<br />

6<br />

11<br />

50 100<br />

£0.27<br />

15 25<br />

£0.38<br />

25 45<br />

£0.39<br />

Emcelle Tocopherol 0.02 0.05 1 2<br />

(ml)<br />

£0.03<br />

£0.27<br />

El-E-Vite 35 80 170 325<br />

£0.06<br />

£0.56<br />

*Based on current retail prices, March ‘04<br />

Toxicity<br />

175 400<br />

£1.07<br />

44 100<br />

£1.53<br />

80 180<br />

£1.55<br />

3.5 8<br />

£1.08<br />

600 1125<br />

£2.24<br />

600<br />

£1.60<br />

150<br />

£2.30<br />

275<br />

£2.32<br />

10<br />

£1.62<br />

2000<br />

£3.36<br />

Toxicity has not been demonstrated in ruminant or equine species. Both acute<br />

and chronic studies of rats, chicks and humans have shown that excessively<br />

high levels can result in undesirable effects; abnormal bone mineralization<br />

and clotting abnormalities, suggestive of metabolic interactions with other fatsoluble<br />

vitamins (D and K). A dietary level of about 75 IU/kg of body weight<br />

is presumed to be the safe upper limit for vitamin E intake.<br />

Further Reading<br />

Dierenfeld, E.S. 1999. Vitamin E: Metabolism, Sources, Unique Problems in<br />

<strong>Zoo</strong> Animals, and Supplementation. Pp 79-82 in: <strong>Zoo</strong> and Wild Animal<br />

Medicine: Current Therapy 4, M.E. Fowler and R.E. Miller, eds, Saunders,<br />

New York.<br />

Dierenfeld, E.S. and M.G. Traber. 1992. Vitamin E Status of Exotic Animals<br />

Compared with Livestock and Domestics. Pp. 345-360 in: Vitamin E in Health<br />

and Disease, L. Packer and J. Fuchs, eds. Marcel Dekker, Inc., New York<br />

191

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