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Mirror-touch synaesthesia: the role of shared ... - UCL Discovery

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131<br />

Chapter 7<br />

Figure 7.1 Summary <strong>of</strong> cTBS and task protocol. Participants completed a samedifferent<br />

auditory emotion (Experiment 1) or identity (Experiment 2) matching task.<br />

Both experiments consisted <strong>of</strong> three testing sessions conducted over three nonconsecutive<br />

days. At each testing session one <strong>of</strong> <strong>the</strong> three brain regions was<br />

stimulated (rSI, rPM or <strong>the</strong> vertex). In each session, <strong>the</strong> task was completed prior to<br />

and 5 minutes following cTBS to each site. The 5 minute rest period was based on<br />

<strong>the</strong> observed time course <strong>of</strong> effects seen in <strong>the</strong> motor cortex. During <strong>the</strong> task, trials<br />

began with a fixation cross followed by <strong>the</strong> presentation <strong>of</strong> a prime emotion via<br />

headphones. Non-verbal auditory emotions <strong>of</strong> amusement, sadness, fear or disgust<br />

were used. After 500 milliseconds a second emotional expression was presented<br />

which was ei<strong>the</strong>r <strong>the</strong> same or different from <strong>the</strong> target. In experiment 1, participants<br />

were asked to indicate whe<strong>the</strong>r <strong>the</strong> emotional expression was <strong>the</strong> same or different to<br />

<strong>the</strong> prime using a key press. In experiment 2, a new group <strong>of</strong> participants were asked<br />

to indicate whe<strong>the</strong>r <strong>the</strong> emotional expressions were produced by <strong>the</strong> same or different<br />

person. The need for speed and accuracy were emphasised.<br />

TMS parameters and coregistration<br />

TMS was delivered via a figure <strong>of</strong> eight coil with a 70mm diameter using a<br />

Magstim Super Rapid Stimulator (Magstim, UK). An <strong>of</strong>fline cTBS paradigm was<br />

used, which consisted <strong>of</strong> a burst <strong>of</strong> 3 pulses at 50Hz repeated at intervals <strong>of</strong> 200ms for<br />

20 seconds, resulting in a total <strong>of</strong> 300 pulses. This paradigm was used to prevent any<br />

influence <strong>of</strong> online auditory and proprioceptive effects <strong>of</strong> TMS on task performance

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