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DRAFT Australian Dietary Guidelines - Eat For Health

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pressure, and the effect is greater in those with hypertension than in those with normal blood<br />

pressure [551-554].<br />

There is evidence of a probable association between a diet low in sodium and a reduction in blood<br />

pressure in children up to 18 years of age (Grade B, Section 13.2 in Evidence Report [14]) [553,<br />

557, 558].<br />

The <strong>Dietary</strong> <strong>Guidelines</strong> for Americans, 2010 draw similar conclusions regarding the relationship<br />

between sodium and blood pressure. They state ‘a strong body of evidence has documented that<br />

in adults, as sodium intake decreases, so does blood pressure. A moderate body of evidence has<br />

documented that as sodium intake decreases, so does blood pressure in children, from birth to 18<br />

years of age’ [143]. They also note that people with hypertension, diabetes and chronic kidney<br />

disease are more sensitive to sodium than healthier younger people, and that sensitivity to sodium<br />

increases with age.<br />

Cardiovascular disease: Despite extensive research on the relationship between sodium and<br />

blood pressure, few long term studies have examined changes in sodium intake and changes in<br />

cardiovascular morbidity and mortality. Past studies have mainly included subjects with<br />

hypertension. The evidence suggests that reducing sodium intake by about 1,000mg/day is<br />

associated with reduced risk of cardiovascular events (Grade C, Section 13.4 in Evidence Report<br />

[14]) [552, 559-564]. The results are consistent with results from drug trials that have shown that<br />

reductions in high blood pressure also lead to reductions in adverse cardiovascular outcomes<br />

[565, 566].<br />

3.2.2.2 Cancer<br />

Evidence of a probable association between consumption of salt and salt-preserved foods with<br />

gastric cancer was found in the systematic review prepared as the background paper for the Joint<br />

WHO/FAO Expert Consultation on diet, nutrition and prevention of chronic diseases [567]. This<br />

association was described as convincing by the WCRF [42]. The WCRF also reported convincing<br />

evidence of an association between processed meats (meat preserved by smoking, curing, salting<br />

or addition of chemical preservatives such as nitrites) and increased risk of colorectal cancer [42]<br />

but it is unclear whether the responsible factor in the food is the salt, other components such as<br />

nitrites, or a combination of these factors.<br />

3.2.2.3 Other conditions<br />

Bone health: Evidence suggesting an association between a low sodium diet and markers of bone<br />

health in postmenopausal women is inconclusive (Section 13.3, Evidence Report [14]).<br />

<strong>DRAFT</strong> <strong>Australian</strong> <strong>Dietary</strong> <strong>Guidelines</strong>- December 2011 84

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