Environmental and Molecular Mutagenesis - Legacy Tobacco ...

222 1989 EMS Abstracts «_- ~,,,E:- - -
Notes gation of the best pez'imental conditions of mouse testes
chro :aosotnal assajr . .~..~the first part of experiment according
to an orthogonal design,three factors including dosa„e
of colchicine,effective time of colchicine .nd time of
sucrifice of mouse(8time point~ during 24 hoars) are stuuied
at c: nixin- level of L 32 (8x4 ) design . t)e criteria
adooted is the number of metaphase I emer . ;,ed under every
1J'!,) fields of hi„h power version . In the sen - .' r :rt :~.' .
experiment,Tl,I mice were treated with :Zitomycit . J and then
sacrificed separately after 1,3,j,9,9 t.nd 11 days,the aberration
frequency of 100 metaphase I was an,3ljsed of each
,nouse . The result demu .sir :.tnd that no stu;istical si ;;nificant
effect upon the frequoncy o° ^let-tphase i were found
b,j tlte three factors mentioned sbove and -ire-itive result
could be abt-,ined it 5-1} d--i,is n-fter treltmer.t,but the hi ;-hest
r-~te o f chroc,osor :r_il .berr .ition is found at tce 1 1 th dkj .
http://legacy.library.ucsf.edu/tid/clb93d00/pdf
THE RESEARCH OF LETHAL Nl!TATION OF
SODII'N FLUORIDE PSI\G SEX-LIM1'KF .D RECESSIVF LETHAL (S1 .RL)
B .Q .Xieo, N .C,2hu and Q .X .2hang
Guuugzhou Health and Anti-epidemic Station,Guengzhou,GuangDong,China
F :uurirle is an e>sential element for human beings,overta{ .ing and undertaking
wilt rarnse some tadr effect .Nany countries have increased fluoride content in
drinking water . The purposr of this research is to determine if fluoride can
imrse leUral mutntion under certain dosage .lhe test use two strains of Drosophiln
melauognster, Oregon K and Ba>r .The e .