document title / titre du document TRP W ORK PLAN ... - emits - ESA

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TRP Work Plan 2005-2007 Description of Activities TEC-SB/7935/dc 12/Feb/09 3.6 - Instrumentation for Life Science TRP Reference: Title: T307-05MM Immuno-Biochemical Analyser In-situ ISS Bio-chemical analysis has been recognized a high priority since many years. Results would then become available in real time, drawbacks of cryo-preservation would be avoided (download weight, biochemical degradation). Previous attempts to adapt ground clinical analyzers for space use didn't turn out positive results. Hence in the previous TRP, it was decided to explore a technology concept for a ISS-compatible biochemical analyser. Out of this activity, two major technologies have been confirmed or adapted:- a new microtiter plate (37.5 mm x 20mm 96 reaction wells) with capillary distribution (microgravity compatible) to be used for bio-chemical measurements,- a Two-Photon excitation (TPX) reader, combined with optical pressure pumping, has been validated on above microtiter plate, making it suitable for immuno-chemistry measurements. The aim of this activity is to develop the set of enabling technologies for a ISS-compatible biochemical analyser in a mid-term future to measure the classes of biochemicals required by ISS physiology research or astronaut medical follow-up. Deliverables: Full technology concept of a ISS-compatible biochemical analyzer, test adaptation procedures, evaluation results. Current TRL: TRL1 Target TRL: TRL3 Application Need/Date: TRL5 > 2010 Application/Mission: ISS/Aurora Medical Contract Duration: 24 months SW Clause : - Dossier0 Ref.: T-1306 Consistency with Harmonisation Roadmap and Conclusions: TRP Reference: T307-09MM Title: Virtual reality stimulator Cognitive neurophysiology is identified as one of the research themes of interest for the ISS. Besides electroencephalography and electromyography, it requires neurosensory stimulators, amongst them the visual/aural ones. Up to know, because computer power was limited, virtual reality generators for neurophysiology were custom-designed, closed systems, used only for one experiment. Moreover, it was not possible to make easy and simple modification of the protocols as scientists usually need it, this instead required major software and hardware redesigns. Making use of the enhanced capabilities of computers and virtual reality devices, the proposed activity aims at studying the enabling technologies for the realization of a multi-purpose, flexible Virtual-Reality generator for cognitive-neurophysiology, that could be used over several ISS increments by a the wide community of users. Deliverables: Documentation, enabling technologies and software for multipurpose virtual reality generator, and evaluation report. Current TRL: TRL1 Target TRL: TRL2 Application Need/Date: TRL5>2010 Application/Mission: ISS/manned exploration Contract Duration: 18 months SW Clause : - Dossier0 Ref.: Consistency with Harmonisation Roadmap and Conclusions: Page 65 of 227
TRP Work Plan 2005-2007 Description of Activities TEC-SB/7935/dc 12/Feb/09 TRP Reference: Title: T307-15MM Life Support Technology for MISS The aim of the activity is to develop a life support system for small animals with good scientific performance and low logistic load. Typical technologies to be considered include compensation systems for O2 consumption and removal of produced CO2 including recycling methods. Furthermore odour control and interaction with the water supply and the waste collection have to be taken into account. An initial concept phase will be followed by the breadboarding and functional/biological testing of the complete selected concept. Deliverables: Fully functional and verified breadboard of a life support system for small animals. Current TRL: TRL2 Target TRL: TRL3-4 Application Need/Date: TRL5 by 2008 Application/Mission: Photon Contract Duration: 24 months SW Clause : - Dossier0 Ref.: T-1314 Consistency with Harmonisation Roadmap and Conclusions: Page 66 of 227
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