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Examination of Firearms Review: 2007 to 2010 - Interpol

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lood carboxyhemoglobin, and the cause <strong>of</strong> death was re-certified as CO<br />

in<strong>to</strong>xication. A 10-year retrospective review conducted on all non-fire related<br />

CO deaths au<strong>to</strong>psied (n = 94) in the U.S. from 1994 <strong>to</strong> 2003, along with an<br />

extensive literature review, indicated no previously reported cases <strong>of</strong> fatal CO<br />

poisoning attributed <strong>to</strong> diesel fuel exhaust.<br />

2.6 Quality Assurance and Accreditation<br />

The implementation <strong>of</strong> quality management systems and accreditation <strong>of</strong><br />

labora<strong>to</strong>ries by regional or national accreditation bodies are intended <strong>to</strong> ensure<br />

that the labora<strong>to</strong>ries are capable <strong>of</strong> providing effective and “fit for purpose”<br />

analytical service <strong>to</strong> the end users. The current status <strong>of</strong> accreditation amongst<br />

labora<strong>to</strong>ries <strong>of</strong>fering drug testing <strong>of</strong> hair was assessed. Although the vast<br />

majority <strong>of</strong> labora<strong>to</strong>ries follow current guidelines (83%), only nine labora<strong>to</strong>ries<br />

were accredited <strong>to</strong> ISO/IEC 17025 standards for hair testing; however, a<br />

significant number <strong>of</strong> labora<strong>to</strong>ries reported that they were in the process <strong>of</strong><br />

developing quality assurance pro<strong>to</strong>cols with a view <strong>to</strong> accrediting their<br />

methods within 2–3 years [210]. Quality assurance in <strong>to</strong>xicological examination<br />

in DUID cases requires efforts from pr<strong>of</strong>essionals <strong>of</strong> different disciplines. In the<br />

quality assurance program <strong>of</strong> Switzerland for labora<strong>to</strong>ries performing<br />

<strong>to</strong>xicological road traffic analyses, a multidisciplinary working group, the Road<br />

Traffic Commission (RTC), was established <strong>to</strong> organize external quality control,<br />

<strong>to</strong> interpret the results <strong>of</strong> these controls, <strong>to</strong> perform audits in the labora<strong>to</strong>ries<br />

and <strong>to</strong> report all results <strong>to</strong> Swiss Federal Road Office [211]. The program<br />

required that all tested drugs and psychoactive substances listed in a federal<br />

instruction as 'zero <strong>to</strong>lerance substances' (THC, morphine, cocaine,<br />

amphetamine, MA, MDMA, and MDEA) and their metabolites <strong>to</strong> be tested<br />

once a year, and all other substances (benzodiazepines, zolpidem,<br />

phenobarbital, etc.) be tested periodically. External audits are performed<br />

triennially, but accredited labora<strong>to</strong>ries can combine the audit with the approval<br />

<strong>of</strong> the Swiss Accreditation Service.<br />

Participation in external quality assurance or pr<strong>of</strong>iciency testing (PT) schemes<br />

is an important part <strong>of</strong> quality management. The Federal Aviation<br />

Administration <strong>of</strong> the U.S. reported the second 7 years <strong>of</strong> their postmortem<br />

<strong>to</strong>xicology pr<strong>of</strong>iciency test program [212]. Twenty-eight survey samples (12<br />

urine, 9 blood, and 7 tissue homogenate) with/without alcohols/volatiles, drugs,<br />

and/or putrefactive amine(s) were submitted, with an average <strong>of</strong> 25<br />

participants reporting their results. Analytes in the survey samples were<br />

643

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