Examination of Firearms Review: 2007 to 2010 - Interpol

with substance abuse histories, with 8 of them being tramadol abusers. A
young man suspected of suffering from a tramadol overdose was found with
tramadol concentration of 8 µg/mL on admission in the ICU; the patient
subsequently died due to severe acute liver failure. Post-mortem toxicology
revealed tramadol concentrations of 5.2 mg/L in blood, 6.5 mg/g in liver and
4.5 mg/g in kidney, with desmethyltramadol detected. This is one of a very few
cases of a lethal poisoning due to tramadol alone [496]. Body fluids and
tissues in eight doxepin-related deaths were investigated [497]. For two cases
of fatal doxepin ingestion and another case of high dosage with advanced
putrefaction, the liver concentration sum (i.e., N-desmethyl metabolite along
with its parent) may be more useful if a fatal ingestion cannot be clearly
separated from a person's medication usage. In another study of 9 cases
related to lethal doxepin intoxication, the concentrations in blood samples from
peripheral vessels was measured to be 1.5-7.0 mg/L, which is in the lowest
quarter of the span of lethal concentrations mentioned in the literature - but the
literature did not specify the location of the blood sample taken [498]. In
reviewing toxicological reports in Canada, there was an increase in the
incidence of findings of acetone in decedents who were taking olanzapine over
the past decade [499]. Olanzapine concentrations were detected in the range
from