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The Design of Diagnostic Medical Facilities where ... - ResearchGate

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shielding for 18 F procedures should be more than adequate for procedures <strong>where</strong> similar quantities <strong>of</strong><br />

radioactivity <strong>of</strong> shorter-lived radionuclides e.g. 11 C, 13 N, 15 O, 82 Rb or those with smaller dose rate constants<br />

e.g. 64 Cu, 68 Ga are administered. However, it should be noted that radionuclides that have higher energy<br />

gamma emissions, in addition to annihilation radiation, might not be adequately shielded in a facility designed<br />

for 18 F (AAPM, 2006).<br />

Radioactivity administration & uptake<br />

<strong>The</strong> amount <strong>of</strong> activity administered for 18 F FDG studies is determined by the mass <strong>of</strong> the patient, the length<br />

<strong>of</strong> the uptake time, and the acquisition mode. Shielding calculations for a facility must therefore take account<br />

<strong>of</strong> the maximum activity to be administered in the facility.<br />

Factors affecting dose rates from PET/CT patients<br />

Following administration <strong>of</strong> the radionuclide, the patient is the primary source <strong>of</strong> radiation. In determining<br />

the radiation dose in areas around the patient, or from an unshielded source, the following points must be<br />

considered:<br />

Dose rate constant<br />

When calculating the shielding requirements for an unshielded 18 F source, a dose rate constant <strong>of</strong> 0.143<br />

μSvm 2 /MBqh should be used. <strong>The</strong> dose rate from an unshielded 37 MBq 18 F point source is<br />

5.3 μSv/h at 1 m (AAPM, 2006).<br />

Attenuation by patient & scanner<br />

Attenuation by patient<br />

Since the body absorbs some <strong>of</strong> the annihilation radiation, the dose rate from the patient is reduced by a<br />

significant factor. <strong>The</strong> AAPM recommends using a dose rate <strong>of</strong> 0.092 μSvm 2 /MBqh from the patient<br />

immediately after administration. This corresponds to an effective body absorption factor <strong>of</strong> 0.36.<br />

Attenuation by scanner<br />

<strong>The</strong> gantry and detectors can provide shielding which may substantially reduce the dose rate at some <strong>of</strong> the<br />

walls <strong>of</strong> the imaging room (AAPM, 2006). This reduction depends on the layout <strong>of</strong> the room, the shielding<br />

characteristics <strong>of</strong> the scanner and the type <strong>of</strong> scanning procedures. Detailed knowledge <strong>of</strong> these is required<br />

to accurately estimate the dose reduction that can be achieved. <strong>The</strong> AAPM report estimates an average dose<br />

reduction <strong>of</strong> 20% which is partially <strong>of</strong>fset by the exposure during the time the patient is being brought into<br />

the room and positioned on the table. <strong>The</strong>y suggest a figure <strong>of</strong> 15% overall reduction as being more realistic.<br />

<strong>The</strong> most conservative approach to shielding requirements will ignore this potential dose reduction.<br />

Physical decay<br />

Decay during uptake or imaging<br />

Because PET radionuclides have short half-lives, the total radiation dose received over a time period t, D(t), is<br />

less than the product <strong>of</strong> the initial dose rate and time [Ḋ(0) x t]. <strong>The</strong> reduction factor, R t<br />

is calculated as<br />

<strong>The</strong> <strong>Design</strong> <strong>of</strong> <strong>Diagnostic</strong> <strong>Medical</strong> <strong>Facilities</strong> <strong>where</strong> Ionising Radiation is used 63

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