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2. HAND HYGIENE AS A QUALITY INDICATOR FOR PATIENT<br />

SAFETY<br />

Patient safety has become the touchstone of contemporary medical care. Medical errors<br />

and adverse events occur with distressing frequency, as outlined persuasively in the United<br />

States Institute of Medicine’s To err is human 700 . HCAIs are second only to medication<br />

errors as a cause of adverse events in hospitalized patients. Hospital infection control<br />

provides a mature template for patient safety with a long track record of research, evidencebased<br />

practice standards, and practice improvement efforts. Moreover, infection control<br />

professionals and hospital epidemiologists have pioneered real-time methods to detect the<br />

occurrence of HCAI and monitor compliance with infection control standards. Nonetheless,<br />

as documented in this report, compliance with hand <strong>hygiene</strong> – the pillar of infection control<br />

– remains woeful in the vast majority of health-care institutions. The current emphasis<br />

on hand <strong>hygiene</strong> by the WHO World Alliance for Patient Safety and many regulatory and<br />

accrediting agencies reflects the slow progress of the health professions in meeting even<br />

modest performance standards.<br />

Donabedian’s quality paradigm of structure, process and outcome 701,702 provides a useful<br />

framework for considering efforts to improve hand <strong>hygiene</strong> compliance. Clearly, if sinks<br />

and alcohol dispensers are not readily accessible (faulty structure) and hand <strong>hygiene</strong> is not<br />

performed (inadequate process), the risk of infection and its attendant morbidity, mortality<br />

and cost (outcomes) will increase. Quality indicators can be developed according to<br />

Donabedian’s framework.<br />

Hazard analysis critical control point is another valuable method to examine the system<br />

of patient care as it relates to hand <strong>hygiene</strong>. Originally developed to provide astronauts with<br />

pathogen-free food, hazard analysis critical control point is now widely employed in good<br />

manufacturing practice, food and drug safety, and blood banking. In brief, the method identifies<br />

error-prone aspects of systems (critical control points), evaluates the risk they pose, and<br />

designs them out. Critical control points are scored according to their probability of occurrence,<br />

probability of avoiding detection, and severity of downstream impact. Failure mode<br />

and effects analysis is closely related to hazard analysis critical control point and is being<br />

exploited increasingly in patient safety. A desirable feature of both hazard analysis critical<br />

control point and failure mode and effects analysis is their emphasis on systems’ errors and<br />

their consequences. An empty alcohol dispenser, failure to educate staff in proper hand<br />

<strong>hygiene</strong> technique, and failure to practise hand <strong>hygiene</strong> after glove removal are serious<br />

failures at key points in the patient-care system. When multidisciplinary care teams map<br />

their institution’s system for hand <strong>hygiene</strong>, they not only identify error-prone critical control<br />

points and barriers to compliance, but also identify which aspects of the system are most<br />

critical to improve and monitor. This collaborative approach to identifying key quality indicators<br />

vastly improves these indicators’ local credibility and relevance and provides a guide<br />

to ongoing improvement and auditing efforts.<br />

Failures at critical control points in the hand <strong>hygiene</strong> system can be seen as problems in<br />

the reliability of the system. The concept of reliability is the bedrock of modern manufacturing<br />

(for example, it transformed the quality of automobile production) but has been applied<br />

to health care only recently. Reliability looks at the defect or failure rate in key aspects of<br />

production (i.e. patient care). Industry often seeks to achieve defect rates of one per million<br />

or less (a component of so-called six-sigma reliability). While such a high degree of reliability<br />

seems impossible in many aspects of health care, it is worth noting that most institutions<br />

have hand <strong>hygiene</strong> defect rates of six per ten opportunities or greater. Moreover, these rates

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