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Table I.21.1:<br />

<strong>Hand</strong> <strong>hygiene</strong> research agenda (Cont.)<br />

Area<br />

Laboratorybased<br />

and<br />

epidemiological<br />

research and<br />

development<br />

In both developed and developing countries<br />

Develop experimental models for the study of crosscontamination<br />

from patient to patient and from environment<br />

to patient<br />

Develop new protocols for evaluating the in vivo efficacy of<br />

agents considering, in particular, short application times and<br />

volumes that reflect actual use in health-care facilities<br />

Monitor hand <strong>hygiene</strong> adherence by using new devices or<br />

adequate surrogate markers, allowing frequent individual<br />

feedback on performance<br />

Evaluate the type of surgical hand antisepsis in the different<br />

countries with a standardized protocol to define the status quo<br />

and compliance with recommendations among surgeons<br />

Determine the percentage increase in hand <strong>hygiene</strong><br />

adherence required to achieve a predictable risk reduction<br />

in infection rates<br />

Generate more definitive evidence for the impact on infection<br />

rates of improved adherence to recommended hand <strong>hygiene</strong><br />

practices<br />

Provide cost–effectiveness evaluation of successful and<br />

unsuccessful promotion campaigns<br />

Conduct further studies to determine the consequences of<br />

soap contamination<br />

Conduct further in vitro and in vivo studies of both alcoholbased<br />

formulations and antimicrobial soaps to establish the<br />

minimal level of virucidal activity that is required to interrupt<br />

direct contact transmission of viruses in health-care settings<br />

Evaluate the effectiveness of handrubbing or washing to<br />

interrupt transmission of pathogens such as noroviruses<br />

Review evidence on reduced susceptibility to antiseptic<br />

agents and evaluate whether or not resistance to antiseptics<br />

may influence the prevalence of antibiotic resistant strains<br />

Evaluate the type of handrub available in the different<br />

countries with a standardized protocol to define the status<br />

quo<br />

The number of positive cultures of tap water at the sink for<br />

Pseudomonas aeruginosa and the number of positive hand<br />

cultures with selective cultures for non-fermenting Gramnegative<br />

bacteria<br />

More focus on<br />

developing countries

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