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particularly when resources are limited, cannot be recommended at present. Whether the<br />

use of basic, oil-containing products, not specifically manufactured for hand skin protection,<br />

would have similar efficacy as currently available manufactured agents remains to be<br />

determined.<br />

Frequent wearing of gloves can increase the risk of skin problems. In a study among<br />

healthy volunteers, when a moisturizer was applied prior to wearing occlusive gloves there<br />

was a statistically significant improvement in skin hydration 473 . More recently, an examination<br />

glove coated with aloe vera resulted in improved skin integrity and decreased erythema<br />

in 30 women with occupational dry skin 474 . Nevertheless, such products cannot yet be<br />

recommended because field trials, larger sample sizes and cost analyses are needed.<br />

In addition to evaluating the efficacy and acceptability of hand-care products, product<br />

selection committees should inquire about potential deleterious effects that oil-containing<br />

products may have on the integrity of rubber gloves and on the efficacy of antiseptic agents<br />

used in the facility 13,417 , as well as the fact that, as previously mentioned, most of these<br />

products are not sterile and can easily become contaminated.<br />

13. FACTORS TO CONSIDER WHEN SELECTING HAND<br />

HYGIENE PRODUCTS<br />

To achieve a high rate of hand <strong>hygiene</strong> adherence, HCWs need education, clear guidelines,<br />

and some understanding of infectious disease risk, and acceptable hand <strong>hygiene</strong><br />

products 134,262,454,455,459,475-477 . The selection of hand cleansing agents is a key component of<br />

hand <strong>hygiene</strong> promotion, and at the same time a difficult task. The selection strategy requires<br />

the presence of a multidisciplinary team (e.g. infection control professionals, administrative<br />

staff, pharmacists and behavioural scientists) and efforts to evaluate factors related to hand<br />

cleansing agents and to conduct clinical pilot projects to test these factors 1,7,16,277,456,478 The<br />

major determinants for product selection are antimicrobial profile and user acceptance. The<br />

antimicrobial efficacy of hand <strong>hygiene</strong> agents is provided by in vitro and in vivo studies (see<br />

Part I, Section 8) which are reproducible and can be generalized. Pilot studies aiming to help<br />

select products at the local level should mainly concentrate on user acceptability issues.<br />

Other aspects such as tolerance, availability, storage and costs should also be addressed on<br />

a local basis to guarantee feasibility and sustainability.<br />

13.1 PILOT TESTING<br />

Pilot testing to assess acceptability is strongly recommended before final selection.<br />

Characteristics that can affect HCWs’ acceptance of a hand <strong>hygiene</strong> product include dermal<br />

tolerance and skin reactions to the product, and its fragrance, consistency and colour 155,445,456 .<br />

Structured self-administered questionnaires may be useful tools to assess HCWs’ acceptability<br />

of hand <strong>hygiene</strong> products. Such tools should be adapted to the local setting because of<br />

differences in sociocultural backgrounds, climate and environmental conditions, and clinical<br />

practices among users. For an efficient comparison, each product should be tested by<br />

different users for at least two to three weeks. Skin reactions to hand <strong>hygiene</strong> products may<br />

be increased by low relative humidity. Therefore, dry weather, e.g. during winter months in<br />

the northern hemisphere, should be taken into account during pilot testing; the introduction<br />

of new products during dry periods, with low relative humidity, should be avoided. Dryness<br />

and irritation should be assessed with sufficient numbers of HCWs to ensure that the results

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