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Table I.9.7:<br />

Efficacy of surgical handrub solutions in reducing the release of resident skin<br />

flora from clean hands<br />

Rub<br />

n-Propanol<br />

Isopropanol<br />

Isopropanol + chlorhexidine gluc. (m/V)<br />

Ethanol<br />

Concentration a<br />

(%)<br />

Time<br />

(min)<br />

Mean log reduction<br />

Immediate Persistent (3h)<br />

60 5 2.9 b 1.6 b<br />

5 2.7 b NA<br />

5 2.5 b 1.8 b<br />

5 2.3 b 1.6 b<br />

3 2.9 c NA<br />

3 2.0 b 1.0 b<br />

1 1.1 b 0.5 b<br />

90 3 2.4 c 1.4 c<br />

80 3 2.3 c 1.2 c<br />

70 5 2.4 b 2.1 b<br />

5 2.1 b 1.0 b<br />

3 2.0 c 0.7 c<br />

3 1.7 c NA<br />

3 1.5 b 0.8 b<br />

2 1.2 0.8<br />

1 0.7 b 0.2<br />

1 0.8 NA<br />

60 5 1.7 1.0<br />

70 + 0.5 5 2.5 b 2.7 b<br />

2 1.0 1.5<br />

95 2 2.1 NA<br />

85 3 2.4 c NA<br />

80 2 1.5 NA<br />

70 2 1.0 0.6<br />

95 + 0.5 2 1.7 NA<br />

Ethanol + chlorhexidine gluc. (m/V) 77 + 0.5 5 2.0 1.5 d<br />

70 + 0.5 2 0.7 1.4<br />

Chlorhexidine gluc. (aq. Sol., m/V) 0.5 2 0.4 1.2<br />

Povidone-iodine (aq. Sol., m/V) 1.0 5 1.9 b 0.8 b<br />

Peracetic acid (m/V) 0.5 5 1.9 NA<br />

Rotter M, reprinted with permission from 1.<br />

NA = not available.<br />

a volume/volume (V/V) unless otherwise stated.<br />

b Tested according to Deutsche Gesellschaft fur Hygiene and Mikrobiologic (DGHM), German Society of Hygiene and<br />

Microbiology.<br />

c Tested according to European Standard prEN.<br />

d After 4 h.

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