ultrasound diagnosis of fatal anomalies

CHROMOSOMAL DISORDERS
Fig. 9.10 Triploidy. Unilateral multicystic renal dysplasia
in a case of triploidy at 17+1weeks.
Fig. 9.11 Triploidy. Genitals in a fetus with 69,XXX
with hypertrophy of the clitoris at 21+3weeks.
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the pregnancy, she should be warned of the high
risk of developing preeclampsia and hyperthyroidism.
Hyperemesis gravidarum and theca
lutein cysts of the ovaries are frequent. The β-
HCG level is increased, but only in 80% of cases in
case of a partial mole. Cesarean section on the
basis of a fetal indication should be avoided.
Procedure after birth: Intensive medical measures
are not indicated.
Prognosis: The pregnancy usually ends with an
early miscarriage. Otherwise intrauterine
demise or death in the early neonatal stage is the
general outcome. In case of mosaic, survival into
early childhood is rare, with severe mental retardation.
Information for the parents: The risk of recurrence
is not increased.
References
Beinder E, Voigt HJ, Jager W, Wildt L. Partial hydatidiform
mole in a cytogenetically normal fetus. Geburtshilfe
Frauenheilkd 1995; 55: 351–3.
Benacerraf BR. Intrauterine growth retardation in the
first trimester associated with triploidy. J Ultrasound
Med 1988; 7: 153–4.
Blaicher W, Ulm B, Ulm MR, Hengstschlager M,
Deutinger J, Bernaschek G. Dandy–Walker malformation
as sonographic marker for fetal triploidy. Ultraschall
Med 2002; 23: 129–33.
Harper MA, Ruiz C, Pettenati MJ, Rao PN. Triploid partial
molar pregnancy detected through maternal serum
alpha-fetoprotein and HCG screening. Obstet Gynecol
1994; 83: 844–6.
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