ultrasound diagnosis of fatal anomalies

SOFT MARKERS OF CHROMOSOMAL ABERRATIONS
Fig. 10.11 Bilateral cystic lesions of the choroid
plexus, at 16 +2 weeks. Normal karyotype. A healthy
infant was born at the due date.
Fig. 10.12 Bilateral cysts of the choroid plexus.
Fetus with trisomy 18 at 22 +5 weeks.
1
2
3
4
5
Procedure after birth: Ultrasound examination
of the skull is advisable, to demonstrate normal
findings and reassure the parents.
Prognosis: In the absence of other anomalies,
the rate of chromosomal aberrations lies between
one in 150 and one in 400. It is unimportant,
whether the cysts are unilateral or bilateral.
In the presence of associated anomalies, the rate
of chromosomal disorders increases considerably.
Isolated plexus cysts do not interfere with
the infant’s further development in any way.
References
Bakos O, Moen KS, Hansson S. Prenatal karyotyping of
choroid plexus cysts. Eur J Ultrasound 1998; 8:
79–83.
Benacerraf BR. Asymptomatic cysts of the fetal choroid
plexus in the second trimester. J Ultrasound Med
1987; 6: 475–8.
Bollmann R, Chaoui R, Zienert A, Körner H. Choroid
plexus cysts in the 2nd trimester: an indication for
trisomy 18. Zentralbl Gynäkol 1992; 114: 171–4.
Chudleigh P, Pearce JM, Campbell S. The prenatal diagnosis
of transient cysts of the fetal choroid plexus.
Prenat Diagn 1984; 4: 135–7.
Ghidini A, Strobelt N, Locatelli A, Mariani E, Piccoli MG,
Vergani P. Isolated fetal choroid plexus cysts: role of
ultrasonography in establishment of the risk of
trisomy 18. Am J Obstet Gynecol 2000; 182: 972–7.
Gucer F, Yuce MA, Karasalihoglu S, Cakir B, Yardim T.
Persistent large choroid plexus cyst: a case report. J
Reprod Med 2001; 46: 256–8.
230